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4-benzyloxy phenol used as decolorizers

Publish Time: 2022-08-08     Origin: Site

Depigmentation is the use of depigmentation agents to lighten the dark skin tone at the edge of the vitiligo and bring it closer to the color of normal skin. Generally, high-concentration hydroquinone cream is used externally to kill residual melanocytes to achieve depigmentation.

However, these substances can be partially absorbed through the skin when used externally, and there are many side effects after absorption (central nervous system, liver toxicity, reproductive toxicity, etc.), so depigmentation is only suitable for small areas, and depigmentation treatment is mainly suitable for patients with leukoplakia involving >95% (Decolorization generally does not exceed the size of 1 palm area), otherwise there will be safety risks.

Moreover, depigmentation is suitable for the residual normal pigment cells in the exposed parts, that is to say, for example, most of the face is white, and the remaining small pieces of normal skin color are suitable for depigmentation treatment. However, it should be noted that decolorization of hydroquinone is irreversible! So friends who choose decolorization must consider carefully before deciding.

Common decolorizers used on the market today: monobenzone & more

1. 20% concentration of 4-benzyloxy phenol cream (monobenzone): Monobenzone is used as a topical freckle agent to treat hyperpigmentation, such as various pigmentation spots, age spots, melanoma, etc., with obvious effects.

2. 20% concentration of 4-methoxyphenol cream (hydroquinone monomethyl ether)

The other names of the organic compound 4-benzyloxyphenol are: p-benzyloxyphenol, 4-benzyloxyphenol, hydroquinone monobenzyl ether and monobenzone, which means that they all belong to the same phenol-containing chemical . At present, the phenol decolorizers produced include hydroquinone monobenzyl ether in liquid form and monobenzone in paste form.



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