It has been found that piperine has pigmentation properties on the skin affected by vitiligo after photosynthesizing with previous UVB exposure.Piperine stimulates the activity of melanocytes that induce melanogenesis.Once the condition has improved,piperine uses to be a natural medicine for the treatment of vitiligo in addition to conventional medications.Black pepper piperine is a powerful antioxidant that can reduce oxidative stress on the skin.Bioperine piperine has purifying properties and is usually used in combination with St. John's wort,propolis and calendula extract to treat skin abscesses,acne and oily skin,and piperine 95 can treat skin irritation or small incisions.Pure piperine applied in face masks, acne treatments;cleansing skin toners for impure skins;mouth washes;ointments;post-therapy creams for treatment of vitiligo; massage oils.
Items | Standards | Results | Methods | |
Appearance | Light Yellow Powder | Complied | Organoleptic | |
Particle Size | Pass through 80 mesh | Complied | CP2010 | |
Bulk Density (g/ml) | 0.60g//ml | Complied
| CP2010 | |
Loss on Drying | ≤1.0% | 0.14% | USP33 | |
Ash Content | ≤1.0% | 0.45% | USP33 | |
Piperine | ≥95.0% | 96.17% | HPLC | |
Pesticide Residue | USP Standard | Complied | GC-MS | |
Heavy Metals | ≤10ppm | Complied
| USP33 | |
Lead | ≤1.0ppm | Complied
| USP33 | |
Arsenic
| ≤1.0ppm
| Complied
| USP33 | |
Mercury | ≤0.1ppm
| Complied
| USP33 | |
Cadmium | ≤1.0ppm
| Complied
| USP33 | |
Microbiological Specifications | ||||
Total Aerobic (CFU/g)
| ≤1000
| Complied
| USP33 | |
Mold and Yeast (CFU/g) | ≤100 | Complied | USP33 | |
Coliform
| Negative | Negative
| USP33 | |
Salmonella
| Negative
| Negative
| USP33 | |
S. Aureus | Negative
| Negative
| USP33 | |
E.coli testing | Negative
| Negative
| USP33 | |
Statements | ||||
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