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Tetrapeptide-30

Product Description

Tetrapeptide-30 is a new peptide that can balance skin tone.

There are a variety of mechanisms for brightening skin tone,including reducing or inhibiting tyrosinase activity, preventing the transfer of melanin to keratinocytes and inhibiting melanocyte activation.

Tetrapeptide in skin care to inhibits the up-regulation of matrix metalloproteinase-1 (MMP-1) by skin fibroblasts, which are caused by direct exposure to ultraviolet rays or treatment with an ultraviolet-treated keratinocyte-regulated medium.They are suitable for the treatment of inflammatory skin diseases and as active ingredients in skin care products.

Technical Date

FAQ

★What is Tetrapeptide-30?

Tetrapeptide‑30 is a synthetic bioactive cosmetic peptide mainly used in high‑end skincare formulations. It works by regulating melanin production and transfer, helping to improve uneven skin tone, fade dark spots and dullness, and enhance overall skin brightness with gentle and stable effects.

★What are the main skincare benefits of Tetrapeptide-30?

This peptide effectively brightens dull skin, reduces the appearance of dark spots, sun spots and post‑inflammatory hyperpigmentation, inhibits excessive melanin synthesis, evens skin tone, and supports skin barrier health. It delivers mild brightening results without strong irritation, making it suitable for long‑term use in daily skincare products.

★What is the recommended usage rate of Tetrapeptide‑30 in cosmetics?

The typical recommended concentration for Tetrapeptide‑30 in cosmetic formulations is 0.001% – 0.01% (10–100 ppm). It can be widely applied in serums, essences, creams, lotions, facial masks and eye care products to achieve ideal brightening and anti‑pigmentation effects.

★Is Tetrapeptide‑30 suitable for sensitive skin?

Yes, Tetrapeptide‑30 is mild, non‑irritating and well‑tolerated by most skin types, including sensitive skin. It does not cause obvious redness, peeling or sensitization, which makes it a safe and popular brightening ingredient for gentle and effective skincare formulas.

★What pH range is Tetrapeptide‑30 stable in?

Tetrapeptide‑30 performs stably in formulations with a pH range of 4.5 – 7.0, and the optimal pH range for maintaining its activity is 5.0 – 6.5. It is compatible with most conventional water‑based, gel and emulsion systems under appropriate conditions.

★Can Tetrapeptide‑30 be used with other active ingredients?

Tetrapeptide‑30 has excellent compatibility and can be used together with many common cosmetic actives such as niacinamide, alpha arbutin, hyaluronic acid, vitamin C derivatives and other peptides. There are no known major incompatibilities with mainstream cosmetic raw materials, allowing flexible formula combination.

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E-mail： alexxue@zhenyibio.com

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Why Choose Us

Innovative Bio-active Enhancement Technology

Beyond simple extraction, ZHENYIBIO masters Enzymatic Hydrolysis and Liposomal Encapsulation to optimize the bio-availability of plant actives. Our in-house R&D team, led by industry PhDs, ensures that every batch of Glutathione or Centella Asiatica Extract meets the highest molecular stability standards.

Controlled Source & Farm-to-Lab Traceability

We operate our own botanical planting bases, ensuring 100% control over raw material quality from the seed. This vertical integration guarantees a stable, year-round supply and full traceability, helping you meet the strict transparency demands of modern "Clean Beauty" consumers.

Global Standards & GMP-Certified Excellence

Quality is our identity. ZHENYIBIO operates under strict GMP and ISO 9001 standards. All products are backed by comprehensive documentation, including COA, MSDS, and HPLC test reports, ensuring seamless compliance for EU (CPNP) and US (MoCRA) market entries.

Consultative Technical & Logistic Support

We don't just sell ingredients; we provide solutions. Our technical team offers formulation guidance to solve compatibility issues, while our global logistics network ensures fast, secure delivery to 50+ countries. Your success is our primary KPI.

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FAQs

How does ZHENYIBIO ensure the oxidative stability of whitening actives in water-based formulations?

We have developed a proprietary Anti-oxidation Stabilization System specifically designed for oxidation-prone active ingredients (such as glutathione). By controlling residual heavy metals in the raw materials—the primary catalysts for oxidation—and recommending a complementary chelating agent regimen, we ensure that the ingredients remain free from browning over extended periods within a pH range of 5.0 to 7.0.

Are your botanical brightening extracts compatible with high-concentration electrolytes?

Our plant extracts undergo a multi-stage refining process to remove the majority of inorganic salts and impurities; as a result, they exhibit excellent compatibility within serum formulations containing thickeners or high concentrations of electrolytes, without giving rise to flocculation or phase separation.

What technologies does ZHENYIBIO use to improve the skin penetration of plant-derived actives?

For large-molecule plant-derived active ingredients, we employ Liposomal Encapsulation and Micronization technologies. These techniques significantly reduce particle size, enabling active ingredients—such as Alpha-Arbutin—to more easily penetrate the stratum corneum and reach the areas where melanocytes are concentrated.

Can you provide In-vitro or In-vivo efficacy data for your whitening product line?

Yes. In addition to providing standard TDS documents, we can—upon request—supply data from Tyrosinase Inhibition Tests as well as Human Patch Test reports to support clinical claims regarding the "whitening efficacy" of your finished products.

Do ZHENYIBIO whitening ingredients meet the regulatory requirements of EU and North America?

Fully Compliant. Our products strictly adhere to both EU (Regulation EC No 1223/2009) and US MoCRA standards. A complete Certificate of Analysis (COA) is provided for every batch of raw materials, ensuring that levels of heavy metals, microbial contaminants, and residual solvents remain well below international regulatory limits.

Are your products "Clean Beauty" compliant (Vegan, Non-GMO, Cruelty-Free)?

Yes. As experts in Natural Plant Actives, we pledge that all our ingredients are derived from sustainable plant sources, contain no animal-derived components, involve no animal testing, and are accompanied by comprehensive traceability statements—empowering your brand to enter the clean beauty sector.

How do you guarantee a stable supply of botanical raw materials regardless of seasonal changes?

ZHENYIBIO maintains its own proprietary botanical cultivation bases. Through controlled environments and standardized harvesting processes, we are able to not only guarantee year-round stock availability but also ensure a high degree of consistency in the content of active ingredients—such as Glabridin—across different production batches.

Can ZHENYIBIO develop customized ingredient concentrations for specific brand requirements?

We can provide customized Standardized Extracts tailored to our clients' specific needs. Whether you require high-purity active monomers or blended ingredients in specific ratios, our R&D laboratory is equipped to make precise adjustments to meet your exact formulation requirements.