Nicotinamide Mononucleotide Powder

Beta Nicotinamide Mononucleotide Description

Aging is a natural process. Humans cannot avoid aging, but we can delay the arrival of mitigating ageing through scientific means. In the process of scientists' anti-aging research, nicotinamide adenine dinucleotide (NAD+) is the key target of anti-aging discovered so far. nicotinamide adenine dinucleotide nad+ exists in every living cell, it is closely related to energy supply and DNA repair, nad metabolism plays a very important role in the health and maintenance of cells. With age, The levels of nad+ in human body will slowly decrease, and people will begin the process of aging. That is to say, if you want to fight aging, increasing the level of NAD+ is one of the effective ways.

But NAD+ cannot be replenished directly. Because NAD+ far exceeds the upper limit of the small molecular weight, it is a molecule with a larger molecular weight, and people cannot directly absorb it by the intestinal wall after eating NAD+. Therefore, as nad+ precursors, NMN is a natural compound with a small molecular weight, which can effectively enter cells and be absorbed by the human body, increasing nad levels. At present, more than 30 countries around the world have added new clinical trials related to nmn supplements, related experiments data show that nmn improved the aging of multiple tissues and organs including heart, intestine, bone marrow, nerve myelin, skeletal muscle, etc.

NMN nicotinamide mononucleotide plays an important role in human cell energy production and participates in the synthesis of intracellular NAD (nicotinamide adenine dinucleotide,an important coenzyme for cell energy conversion).NMN nicotinamide mononucleotide plays an important role in the energy production of human cells.It is involved in the synthesis of NAD in the cell (nicotinamide adenine dinucleotide,an important coenzyme for cell energy).

In 2013, the team of Professor David Sinclair of Harvard Medical School published a paper in "Cell": In their clinical trials, one week after using NMN to increase NAD+, 22-month-old mice (equivalent to 60-years-old older adults) and previously different mice, and 6-month-old mice (equivalent to 20-years-old young humans) have similar levels of key indicators such as mitochondrial homeostasis and muscle health.

In April 2021, a research team led by Japanese scholar Shinichiro Imai released the results of the first clinical study of NMN, confirming the practical effects of NMN on the human body: oral administration of nmn can enhance insulin sensitivity, improve muscle structure and weight. plastic-related gene expression, and no adverse reactions were found throughout the study. So this approved NMn is safe and effectively for human body.

Beta nicotinamide mononucleotide itself is a substance in the cell body and is very safe as a medicine or best health care product like nmn supplement.NMN nicotinamide mononucleotide is a monomer molecule with obvious anti-aging effects,so it can be used as a cosmetic raw material.

In addition, nmn and nicotinamide riboside have been found to include: repair DNA damage, activate longevity genes, improve sleep, hangover and liver protection, help treat hair loss, relieve muscle aging, improve female reproductive capacity, prevent Alzheimer's, Repairs kidney damage, maintains vascular health, protects the optic nerve, and more.

Nmn Nicotinamide Mononucleotide Technical Date

★What is the source and production process of your Nicotinamide Mononucleotide Powder?

Our NMN adopts bio-fermentation process with non-GMO raw materials, green and safe, which is different from chemical synthesis, and more suitable for sensitive skin formulas.

★What is the appearance and purity of your cosmetic Nicotinamide Mononucleotide Powder?

It appears as white or off-white crystalline powder, with purity ≥ 99%, low impurity, stable batch consistency.

★Is Nicotinamide Mononucleotide Powder stable in water-based skincare products?

NMN is moderately stable in water at pH 4.0–6.0 and temperatures below 40°C. However, it can degrade over time when exposed to heat, light, or extreme pH (<3.5 or >7.0). To maximize stability: use chelators (EDTA), add antioxidants (vitamin E, ferulic acid), store in opaque, airless packaging, and avoid high-temperature processing. We provide stability data for 12 months under accelerated conditions.

★Can Nicotinamide Mononucleotide Powder be combined with other active ingredients (vitamin C, retinol, AHAs)?

With Vitamin C (L-ascorbic acid): Avoid direct combination in same aqueous phase (pH conflict and oxidation risk). Use derivatives (SAP, MAP) or separate phases.

With Retinol: Yes, but add antioxidants to prevent NMN degradation.

With AHAs/BHAs: Only if final pH >4.0. Below pH 3.5, NMN hydrolyzes rapidly.

We offer free formulation consulting to help you design compatible systems.

★Is Nicotinamide Mononucleotide Powder approved for cosmetic use in the EU, USA, and China?

EU: NMN is not listed in CosIng as of 2025, but can be used as a novel cosmetic ingredient subject to safety assessment (Article 11). Many EU brands use it as a “functional active”. We can provide a Cosmetic Product Safety Report (CPSR).

USA: NMN is generally recognized as safe (GRAS) for dietary supplements, but for cosmetics, it’s allowed as an ingredient with no specific ban.

China (NMPA): NMN is approved for cosmetic use under IECIC 2021 (INCI: Nicotinamide Mononucleotide) with maximum concentration not specified (typical use 0.1-5%). We provide all registration documents.

Important note: As of 2023, NMN is banned as a dietary supplement ingredient in the US (FDA), but this does not affect cosmetic use.

★What is the recommended dosage of NMN in cosmetic formulations?

Serums & ampoules: 1-5% (for anti-aging/repair effects)

Creams & lotions: 0.5-2% (for daily maintenance)

Masks & patches: 3-5% (short-term intensive treatment)

Eye creams: 0.5-1% (gentle for eye area)

We recommend starting at 1% and conducting stability/patch tests before scaling up.