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Nicotinamide Powder

Product Description

Nicotinamide, is an amide compound of niacin. A white crystalline powder; Odorless or almost odorless, with a bitter taste; Slightly hygroscopic. Soluble in water or ethanol, soluble in glycerol.

Application

1. Biochemical research: Nicotinamide is a nutritional component of tissue culture medium; The clinical medication is vitamin B, used for the treatment of diseases such as pellagra, stomatitis, and glossitis.

2. Nicotinamide plays multiple roles in cosmetics, mainly including moisturizing and moisturizing, whitening, and brightening skin tone. Niacinamide has antioxidant properties and anti-inflammatory effects, improving skin texture, controlling oil, and shrinking pores. Used in hair care to promote scalp blood circulation, healthy hair follicles, promote hair growth, and prevent baldness.

Technical Date

FAQ

★What is the appearance and purity of your cosmetic-grade Nicotinamide Powder?

It appears as white crystalline powder with purity ≥ 99% (HPLC test), low impurity, low nicotinic acid content, and stable batch consistency.

★Is Nicotinamide Powder water-soluble or oil-soluble?

Niacinamide is excellent water-soluble, easy to dissolve in water phase and compatible with most aqueous & emulsified formulas.

★How does Nicotinamide Powder brighten skin?

It inhibits the transfer of melanin from melanocytes to keratinocytes without damaging melanocytes, achieving gentle and long-lasting brightening effect.

★What products is Nicotinamide Powder suitable for?

Whitening serums, oil-control lotions, barrier repair creams, toners, masks, sunscreens, sensitive skin care products and anti-aging cosmetics.

★What is the recommended usage rate of Nicotinamide Powder in formulations?

Daily mild care: 1%–2%

Oil control & brightening: 2%–5%

High-efficiency repair: 5%–10%

★What ingredients can Nicotinamide Powder be compounded with?

It can be combined with vitamin C derivatives, tranexamic acid, arbutin, glabridin, hyaluronic acid, peptides and centella asiatica to enhance efficacy.

★What is the recommended dosage of Niacinamide in cosmetic formulations?

Effective concentration ranges vary by target benefit:

Barrier repair / moisturizing: 2-5%

Skin brightening / hyperpigmentation: 4-5% (studies show 5% effective)

Anti-aging / wrinkle reduction: 3-5%

Sebum control / pore reduction: 2-4%

Anti-acne / anti-inflammatory: 2-5%

General purpose (toners, lotions): 2-3%

Higher concentrations (up to 10%) are safe but may cause mild irritation for some users. For first trials, start at 2-3%. Note: Some markets restrict Niacinamide to ≤5% for leave-on products (check local regulations).

★Is Niacinamide approved for cosmetic use in the EU, USA, and China?

EU: Listed in CosIng with no concentration restriction (typical use ≤5%).

USA: Allowed; FDA considers it safe for cosmetic use.

China (NMPA): Listed in IECIC 2021 (INCI: 烟酰胺) with no maximum concentration specified, but some finished product registration guidelines suggest ≤5% for leave-on.

We provide full registration documents including COA, MSDS, TDS, and China compliance declaration. Note: For export to Japan, Niacinamide is classified as a “quasi-drug” active at certain concentrations; please check local requirements.

Tel：+8615309206328

WhatsApp： +8613572414292

E-mail： alexxue@zhenyibio.com

Phone：+86-029-81294858

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FAQs

How does ZHENYIBIO ensure the oxidative stability of whitening actives in water-based formulations?

We have developed a proprietary Anti-oxidation Stabilization System specifically designed for oxidation-prone active ingredients (such as glutathione). By controlling residual heavy metals in the raw materials—the primary catalysts for oxidation—and recommending a complementary chelating agent regimen, we ensure that the ingredients remain free from browning over extended periods within a pH range of 5.0 to 7.0.

Are your botanical brightening extracts compatible with high-concentration electrolytes?

Our plant extracts undergo a multi-stage refining process to remove the majority of inorganic salts and impurities; as a result, they exhibit excellent compatibility within serum formulations containing thickeners or high concentrations of electrolytes, without giving rise to flocculation or phase separation.

What technologies does ZHENYIBIO use to improve the skin penetration of plant-derived actives?

For large-molecule plant-derived active ingredients, we employ Liposomal Encapsulation and Micronization technologies. These techniques significantly reduce particle size, enabling active ingredients—such as Alpha-Arbutin—to more easily penetrate the stratum corneum and reach the areas where melanocytes are concentrated.

Can you provide In-vitro or In-vivo efficacy data for your whitening product line?

Yes. In addition to providing standard TDS documents, we can—upon request—supply data from Tyrosinase Inhibition Tests as well as Human Patch Test reports to support clinical claims regarding the "whitening efficacy" of your finished products.

Do ZHENYIBIO whitening ingredients meet the regulatory requirements of EU and North America?

Fully Compliant. Our products strictly adhere to both EU (Regulation EC No 1223/2009) and US MoCRA standards. A complete Certificate of Analysis (COA) is provided for every batch of raw materials, ensuring that levels of heavy metals, microbial contaminants, and residual solvents remain well below international regulatory limits.

Are your products "Clean Beauty" compliant (Vegan, Non-GMO, Cruelty-Free)?

Yes. As experts in Natural Plant Actives, we pledge that all our ingredients are derived from sustainable plant sources, contain no animal-derived components, involve no animal testing, and are accompanied by comprehensive traceability statements—empowering your brand to enter the clean beauty sector.

How do you guarantee a stable supply of botanical raw materials regardless of seasonal changes?

ZHENYIBIO maintains its own proprietary botanical cultivation bases. Through controlled environments and standardized harvesting processes, we are able to not only guarantee year-round stock availability but also ensure a high degree of consistency in the content of active ingredients—such as Glabridin—across different production batches.

Can ZHENYIBIO develop customized ingredient concentrations for specific brand requirements?

We can provide customized Standardized Extracts tailored to our clients' specific needs. Whether you require high-purity active monomers or blended ingredients in specific ratios, our R&D laboratory is equipped to make precise adjustments to meet your exact formulation requirements.