Home / Products / Cosmetic Peptide / Palmitoyl Pentapeptide-4

PRODUCTS CATEGORY

Whitening & Lightening Moisturizing Anti-Aging Anti-Oxidant Anti-Inflammatory Tanning Cosmetic Peptide Liposomal Cosmetic Ingredients Natural Ingredients

Share to:

Palmitoyl Pentapeptide-4

Product Description

Palmitoyl Pentapeptide-4 for skin care in anti-wrinkle and anti-aging.Palmitoyl pentapeptide helps reduce the appearance of deep wrinkles significantly, makes skin smoother and softer.It also firms up the skin.The compound supports the three key building blocks that are needed for fresh,youthful skin.pentapeptide 4 helps skin promote natural levels of Collagen,Hyaluronic Acid,and Fibronectin.

Technical Date

FAQ

★What are the key benefits of Palmitoyl Pentapeptide-4?

Palmitoyl Pentapeptide-4 offers benefits such as wrinkle reduction, improved skin elasticity, enhanced firmness, and overall skin rejuvenation. It is particularly effective in anti-aging formulations targeting fine lines and loss of skin structure.

★Why is Palmitoyl Pentapeptide-4 considered a signal peptide?

It is classified as a signal peptide because it can mimic natural biological signals that trigger skin repair and regeneration processes. This signaling function helps activate collagen synthesis and supports skin renewal at a cellular level.

★Is Palmitoyl Pentapeptide-4 safe for cosmetic use?

Palmitoyl Pentapeptide-4 is generally considered safe and well-tolerated in cosmetic formulations. It has a low irritation profile, making it suitable for long-term use in anti-aging skincare products.

★What is the solubility of Palmitoyl Pentapeptide-4?

Palmitoyl Pentapeptide-4 is typically soluble in water or water-based systems, depending on its formulation form. It is often supplied in solution for easier incorporation into cosmetic products.

★What is the maximum permitted concentration for this peptide?

China's historical usage data shows up to 20% in leave-on products. CIR concluded 0.0012% is safe for leave-on and 0.0035% for rinse-off. We recommend following local regulatory limits.

★What is the recommended usage concentration?

Efficacy studies show significant wrinkle reduction at 3-5000 ppm (0.0003%-0.5%). For finished products, 1-7% of a 500ppm peptide solution is recommended. Start at lower concentrations for first formulations.

★Is Palmitoyl Pentapeptide-4 listed in China cosmetic ingredient catalog?

Yes, Palmitoyl Pentapeptide-4 (INCI: Palmitoyl Pentapeptide-4, CAS 214047-00-0) is officially included in China Inventory of Used Cosmetic Ingredients 2021 Edition. It complies with China Cosmetic Safety Technical Specifications, authorized anti-aging peptide raw material, fully eligible for domestic formula filing, global export declaration and anti-wrinkle skincare product registration.

★What anti-aging and repairing effects does Palmitoyl Pentapeptide-4 have?

It is a signal peptide that stimulates fibroblasts to synthesize collagen and elastin. It reduces fine lines and dry wrinkles, firms loose skin, improves skin elasticity, repairs damaged skin barrier, diminishes photoaging marks and smoothens skin texture. It works similarly to matrix protein to delay skin aging without irritation.

★What recommended safe usage dosage of Palmitoyl Pentapeptide-4 in cosmetics?

Common leave-on formula dosage: 0.1%–1.0%. Stable in weak acidic pH systems, low molecular weight for good skin penetration, CIR safety certified, non-irritating and non-sensitizing for long-term daily skincare use.

Tel：+8615309206328

WhatsApp： +8613572414292

E-mail： alexxue@zhenyibio.com

Phone：+86-029-81294858

Related Products

丨丨丨丨丨丨

丨丨丨丨丨丨丨

Why Choose Us

Innovative Bio-active Enhancement Technology

Beyond simple extraction, ZHENYIBIO masters Enzymatic Hydrolysis and Liposomal Encapsulation to optimize the bio-availability of plant actives. Our in-house R&D team, led by industry PhDs, ensures that every batch of Glutathione or Centella Asiatica Extract meets the highest molecular stability standards.

Controlled Source & Farm-to-Lab Traceability

We operate our own botanical planting bases, ensuring 100% control over raw material quality from the seed. This vertical integration guarantees a stable, year-round supply and full traceability, helping you meet the strict transparency demands of modern "Clean Beauty" consumers.

Global Standards & GMP-Certified Excellence

Quality is our identity. ZHENYIBIO operates under strict GMP and ISO 9001 standards. All products are backed by comprehensive documentation, including COA, MSDS, and HPLC test reports, ensuring seamless compliance for EU (CPNP) and US (MoCRA) market entries.

Consultative Technical & Logistic Support

We don't just sell ingredients; we provide solutions. Our technical team offers formulation guidance to solve compatibility issues, while our global logistics network ensures fast, secure delivery to 50+ countries. Your success is our primary KPI.

Company Certificates

FAQs

How does ZHENYIBIO ensure the oxidative stability of whitening actives in water-based formulations?

We have developed a proprietary Anti-oxidation Stabilization System specifically designed for oxidation-prone active ingredients (such as glutathione). By controlling residual heavy metals in the raw materials—the primary catalysts for oxidation—and recommending a complementary chelating agent regimen, we ensure that the ingredients remain free from browning over extended periods within a pH range of 5.0 to 7.0.

Are your botanical brightening extracts compatible with high-concentration electrolytes?

Our plant extracts undergo a multi-stage refining process to remove the majority of inorganic salts and impurities; as a result, they exhibit excellent compatibility within serum formulations containing thickeners or high concentrations of electrolytes, without giving rise to flocculation or phase separation.

What technologies does ZHENYIBIO use to improve the skin penetration of plant-derived actives?

For large-molecule plant-derived active ingredients, we employ Liposomal Encapsulation and Micronization technologies. These techniques significantly reduce particle size, enabling active ingredients—such as Alpha-Arbutin—to more easily penetrate the stratum corneum and reach the areas where melanocytes are concentrated.

Can you provide In-vitro or In-vivo efficacy data for your whitening product line?

Yes. In addition to providing standard TDS documents, we can—upon request—supply data from Tyrosinase Inhibition Tests as well as Human Patch Test reports to support clinical claims regarding the "whitening efficacy" of your finished products.

Do ZHENYIBIO whitening ingredients meet the regulatory requirements of EU and North America?

Fully Compliant. Our products strictly adhere to both EU (Regulation EC No 1223/2009) and US MoCRA standards. A complete Certificate of Analysis (COA) is provided for every batch of raw materials, ensuring that levels of heavy metals, microbial contaminants, and residual solvents remain well below international regulatory limits.

Are your products "Clean Beauty" compliant (Vegan, Non-GMO, Cruelty-Free)?

Yes. As experts in Natural Plant Actives, we pledge that all our ingredients are derived from sustainable plant sources, contain no animal-derived components, involve no animal testing, and are accompanied by comprehensive traceability statements—empowering your brand to enter the clean beauty sector.

How do you guarantee a stable supply of botanical raw materials regardless of seasonal changes?

ZHENYIBIO maintains its own proprietary botanical cultivation bases. Through controlled environments and standardized harvesting processes, we are able to not only guarantee year-round stock availability but also ensure a high degree of consistency in the content of active ingredients—such as Glabridin—across different production batches.

Can ZHENYIBIO develop customized ingredient concentrations for specific brand requirements?

We can provide customized Standardized Extracts tailored to our clients' specific needs. Whether you require high-purity active monomers or blended ingredients in specific ratios, our R&D laboratory is equipped to make precise adjustments to meet your exact formulation requirements.