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Tranexamic Acid Powder

Product Description

Tranexamic acid, also known as tranexamic acid, clotting acid, or hemostatic acid, is a white crystalline powder with no odor. The chemical name is trans 4-aminomethylcyclohexanecarboxylic acid, which is an organic compound with the chemical formula C8H15NO2. It is mainly used as a hemostatic agent.

Tranexamic acid can inhibit fibrinolytic enzymes and has hemostatic, anti allergic, and anti-inflammatory effects.

1. Anti fibrinolytic activity: Tranexamic acid can strongly adsorb to the lysine binding site (LBS) of the fibrinogen affinity site on plasmin and plasminogen, inhibiting the binding of plasmin and plasminogen to fibrin, thereby strongly inhibiting fibrinolysis caused by plasmin. Additionally, in the serum ɑ In the presence of anti fibrinolytic enzymes such as 2-macroglobulin, the anti fibrinolytic effect of tranexamic acid is more pronounced, and the hemostatic effect is more significant.

2. Hemostatic effect: abnormally high levels of plasmin can cause platelet aggregation inhibition and coagulation factor breakdown. Mild hyperthyroidism first leads to the breakdown of fibrin. Therefore, in general bleeding, tranexamic acid can inhibit fibrinolysis and play a hemostatic role.

Technical Date

FAQ

★What is the appearance and purity of your cosmetic-grade Tranexamic Acid Powder?

It appears as white crystalline powder with purity ≥ 99% (HPLC), low heavy metals, low impurity and stable batch consistency.

★Is Tranexamic Acid Powder water-soluble or oil-soluble?

Tranexamic Acid is excellent water-soluble, easy to dissolve in water phase and suitable for various aqueous and emulsified skincare formulas.

★What products is Tranexamic Acid Powder suitable for?

Spot-correcting serums, melasma treatment creams, brightening toners, post-laser repair products, acne mark repair essences, sensitive skin brightening lotions and daily whitening masks.

★What is the recommended usage rate in formulations?

Recommended concentration: 1%–5%

Daily mild brightening: 1%–2%

Melasma & spot fading: 2%–5%

★What pH range is suitable for Tranexamic Acid Powder?

It is stable and effective in pH 5.0–7.5 (weakly acidic to neutral), compatible with most mild skincare formulas.

★How does Tranexamic Acid differ from traditional whitening agents (kojic acid, arbutin, vitamin C)?

Traditional agents work by inhibiting tyrosinase (melanin production). Tranexamic acid works by blocking the plasmin/plasminogen pathway, which reduces the interaction between keratinocytes and melanocytes triggered by UV or hormones. Key differences:

Target: Works upstream of melanin synthesis, preventing the activation signals.

Specialty: Most effective for melasma (especially hormone-related) and UV-induced pigmentation.

Synergy: Works very well with tyrosinase inhibitors for multi-target whitening.

No irritation: Does not cause redness or peeling like high-concentration kojic acid.

★Is Tranexamic acid approved for cosmetic use in the EU, USA, and China?

EU: Listed in CosIng as Tranexamic Acid (CAS 1197-18-8) with no concentration restriction (typical use ≤5%).

USA: Allowed as a cosmetic ingredient; FDA has no specific ban. It is also available as a prescription drug for oral use.

China (NMPA): Listed in IECIC 2021 (INCI: 氨甲环酸) with no maximum concentration specified (typical use ≤5%).

We provide full registration documents including COA, MSDS, TDS, and China compliance declaration. Note: For oral TXA products, additional drug regulations apply. Our cosmetic-grade TXA is for topical use only.

Tel：+8615309206328

WhatsApp： +8613572414292

E-mail： alexxue@zhenyibio.com

Phone：+86-029-81294858

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FAQs

How does ZHENYIBIO ensure the oxidative stability of whitening actives in water-based formulations?

We have developed a proprietary Anti-oxidation Stabilization System specifically designed for oxidation-prone active ingredients (such as glutathione). By controlling residual heavy metals in the raw materials—the primary catalysts for oxidation—and recommending a complementary chelating agent regimen, we ensure that the ingredients remain free from browning over extended periods within a pH range of 5.0 to 7.0.

Are your botanical brightening extracts compatible with high-concentration electrolytes?

Our plant extracts undergo a multi-stage refining process to remove the majority of inorganic salts and impurities; as a result, they exhibit excellent compatibility within serum formulations containing thickeners or high concentrations of electrolytes, without giving rise to flocculation or phase separation.

What technologies does ZHENYIBIO use to improve the skin penetration of plant-derived actives?

For large-molecule plant-derived active ingredients, we employ Liposomal Encapsulation and Micronization technologies. These techniques significantly reduce particle size, enabling active ingredients—such as Alpha-Arbutin—to more easily penetrate the stratum corneum and reach the areas where melanocytes are concentrated.

Can you provide In-vitro or In-vivo efficacy data for your whitening product line?

Yes. In addition to providing standard TDS documents, we can—upon request—supply data from Tyrosinase Inhibition Tests as well as Human Patch Test reports to support clinical claims regarding the "whitening efficacy" of your finished products.

Do ZHENYIBIO whitening ingredients meet the regulatory requirements of EU and North America?

Fully Compliant. Our products strictly adhere to both EU (Regulation EC No 1223/2009) and US MoCRA standards. A complete Certificate of Analysis (COA) is provided for every batch of raw materials, ensuring that levels of heavy metals, microbial contaminants, and residual solvents remain well below international regulatory limits.

Are your products "Clean Beauty" compliant (Vegan, Non-GMO, Cruelty-Free)?

Yes. As experts in Natural Plant Actives, we pledge that all our ingredients are derived from sustainable plant sources, contain no animal-derived components, involve no animal testing, and are accompanied by comprehensive traceability statements—empowering your brand to enter the clean beauty sector.

How do you guarantee a stable supply of botanical raw materials regardless of seasonal changes?

ZHENYIBIO maintains its own proprietary botanical cultivation bases. Through controlled environments and standardized harvesting processes, we are able to not only guarantee year-round stock availability but also ensure a high degree of consistency in the content of active ingredients—such as Glabridin—across different production batches.

Can ZHENYIBIO develop customized ingredient concentrations for specific brand requirements?

We can provide customized Standardized Extracts tailored to our clients' specific needs. Whether you require high-purity active monomers or blended ingredients in specific ratios, our R&D laboratory is equipped to make precise adjustments to meet your exact formulation requirements.