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S Acetyl Glutathione Powder

Product Description

S-Acetyl-L-Glutathione (SAG) is a high-purity, independently synthesized advanced derivative of reduced L-glutathione, featuring optimized molecular structure and superior biochemical stability. Different from conventional glutathione that is easily decomposed and oxidized in the digestive tract and plasma, our self-synthesized SAG adopts exclusive acetylation modification technology on the sulfur atom of the glutathione molecule. This unique structural design effectively shields the active thiol group, preventing degradation during absorption and circulation, and greatly improving lipophilicity and transmembrane absorption efficiency.

As a next-generation cellular antioxidant and detoxification ingredient, SAG delivers significantly higher bioavailability than ordinary oral glutathione. After entering the human body, it can be efficiently converted into active L-glutathione inside cells, rapidly and safely elevating intracellular glutathione levels. It performs core functions including free radical scavenging, oxidative stress relief, cellular damage repair, and systemic toxin metabolism. With stable chemical properties, no irritants, and excellent safety compatibility, independently synthesized SAG is widely applicable in pharmaceutical intermediates, high-end dietary supplements, functional skincare raw materials, and biomedical research fields.

Our S-Acetyl-L-Glutathione is fully independently synthesized with mature and controllable production processes, strict quality inspection standards, stable product purity, and consistent batch quality. It complies with international raw material production specifications, meeting the high-standard application demands of global customers for high-stability, high-activity, and high-purity glutathione derivatives.

Technical Data

FAQ

★What is the difference between S-Acetyl-L-Glutathione powder and L-Glutathione?

S-Acetyl-L-Glutathione is an acetylated form of L-glutathione. The acetyl group is introduced to modify the thiol group of glutathione, with the aim of improving its stability compared with conventional reduced glutathione. This makes S-Acetyl-L-Glutathione an attractive ingredient for supplement and nutraceutical formulations where stability and intracellular glutathione delivery are important considerations.

★Why does S-Acetyl-L-Glutathione powder offer superior oral stability compared to regular reduced glutathione?

The acetyl group attached to the sulfur atom protects the molecule from enzymatic degradation by peptidases in the gastrointestinal tract and liver, allowing it to pass into cells largely intact and directly raise intracellular glutathione levels more effectively than standard reduced glutathione.

★Is S-Acetyl-L-Glutathione powder better than liposomal glutathione?

S-Acetyl-L-Glutathione and liposomal glutathione use different approaches to improve glutathione delivery. S-Acetyl-L-Glutathione is chemically modified through acetylation, while liposomal glutathione uses a lipid-based delivery system. Neither should be considered universally superior because performance depends on formulation design, dosage form, stability, and the intended application.

★What manufacturing and chemical synthesis processes are used for S-Acetyl-L-Glutathione powder?

Commercial S-Acetyl-L-Glutathione is produced through advanced controlled chemical acetylation of reduced glutathione (GSH) under strict anhydrous conditions, followed by multi-step crystallization, purification, and vacuum drying to ensure high stability and export quality.

★What is the purity of S-Acetyl-L-Glutathione powder?

ZHENYIBIO's S-Acetyl-L-Glutathione powder is available in different specifications depending on the manufacturer and application. High-purity commercial materials are commonly offered at around 98%–99% by HPLC. The exact purity, assay method, appearance, and other quality parameters should always be confirmed through the current product specification and CoA.

★Do you provide free samples?

Yes, we provide free samples for testing. Shipping is free within China, while international customers are required to cover shipping costs.

★What documents can you provide?

We can provide COA, MSDS, TDS, Certificate of Origin, and other regulatory or compliance documents as required.

★What certifications does your company have?

ZHENYIBIO certified with ISO22000, Kosher, Halal, and Food Management License. Additional documentation can be provided upon request.

Tel：+8615309206328

WhatsApp： +8615309206328

E-mail： alexxue@zhenyibio.com

Phone：+86-029-81294858

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Why Choose Us

Innovative Bio-active Enhancement Technology

Beyond simple extraction, ZHENYIBIO masters Enzymatic Hydrolysis and Liposomal Encapsulation to optimize the bio-availability of plant actives. Our in-house R&D team, led by industry PhDs, ensures that every batch of Glutathione or Centella Asiatica Extract meets the highest molecular stability standards.

Controlled Source & Farm-to-Lab Traceability

We operate our own botanical planting bases, ensuring 100% control over raw material quality from the seed. This vertical integration guarantees a stable, year-round supply and full traceability, helping you meet the strict transparency demands of modern "Clean Beauty" consumers.

Global Standards & GMP-Certified Excellence

Quality is our identity. ZHENYIBIO operates under strict GMP and ISO 9001 standards. All products are backed by comprehensive documentation, including COA, MSDS, and HPLC test reports, ensuring seamless compliance for EU (CPNP) and US (MoCRA) market entries.

Consultative Technical & Logistic Support

We don't just sell ingredients; we provide solutions. Our technical team offers formulation guidance to solve compatibility issues, while our global logistics network ensures fast, secure delivery to 50+ countries. Your success is our primary KPI.

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FAQs

How does ZHENYIBIO ensure the oxidative stability of whitening actives in water-based formulations?

We have developed a proprietary Anti-oxidation Stabilization System specifically designed for oxidation-prone active ingredients (such as glutathione). By controlling residual heavy metals in the raw materials—the primary catalysts for oxidation—and recommending a complementary chelating agent regimen, we ensure that the ingredients remain free from browning over extended periods within a pH range of 5.0 to 7.0.

Are your botanical brightening extracts compatible with high-concentration electrolytes?

Our plant extracts undergo a multi-stage refining process to remove the majority of inorganic salts and impurities; as a result, they exhibit excellent compatibility within serum formulations containing thickeners or high concentrations of electrolytes, without giving rise to flocculation or phase separation.

What technologies does ZHENYIBIO use to improve the skin penetration of plant-derived actives?

For large-molecule plant-derived active ingredients, we employ Liposomal Encapsulation and Micronization technologies. These techniques significantly reduce particle size, enabling active ingredients—such as Alpha-Arbutin—to more easily penetrate the stratum corneum and reach the areas where melanocytes are concentrated.

Can you provide In-vitro or In-vivo efficacy data for your whitening product line?

Yes. In addition to providing standard TDS documents, we can—upon request—supply data from Tyrosinase Inhibition Tests as well as Human Patch Test reports to support clinical claims regarding the "whitening efficacy" of your finished products.

Do ZHENYIBIO whitening ingredients meet the regulatory requirements of EU and North America?

Fully Compliant. Our products strictly adhere to both EU (Regulation EC No 1223/2009) and US MoCRA standards. A complete Certificate of Analysis (COA) is provided for every batch of raw materials, ensuring that levels of heavy metals, microbial contaminants, and residual solvents remain well below international regulatory limits.

Are your products "Clean Beauty" compliant (Vegan, Non-GMO, Cruelty-Free)?

Yes. As experts in Natural Plant Actives, we pledge that all our ingredients are derived from sustainable plant sources, contain no animal-derived components, involve no animal testing, and are accompanied by comprehensive traceability statements—empowering your brand to enter the clean beauty sector.

How do you guarantee a stable supply of botanical raw materials regardless of seasonal changes?

ZHENYIBIO maintains its own proprietary botanical cultivation bases. Through controlled environments and standardized harvesting processes, we are able to not only guarantee year-round stock availability but also ensure a high degree of consistency in the content of active ingredients—such as Glabridin—across different production batches.

Can ZHENYIBIO develop customized ingredient concentrations for specific brand requirements?

We can provide customized Standardized Extracts tailored to our clients' specific needs. Whether you require high-purity active monomers or blended ingredients in specific ratios, our R&D laboratory is equipped to make precise adjustments to meet your exact formulation requirements.