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Home / News / Betulinic acid: one of the components of Chaga

Betulinic acid: one of the components of Chaga

Views: 2     Author: Site Editor     Publish Time: 2022-09-19      Origin: Site

Important elements in Chaga: polysaccharides

Polysaccharides are a class of complex macromolecular compounds linked by glycosidic bonds. Although polysaccharides are in the form of sugars, they are rarely sourced in food. Expert research shows that polysaccharides can improve human immunity, and the health care effect is 14 times that of Ganoderma lucidum. Polysaccharides have a significant effect on cardiovascular disease and type 2 diabetes. It also acts as an anticoagulant, reducing the stickiness of platelets, making it harder for them to build up in the arterial walls. They have antithrombotic effects and lower blood lipids. Polysaccharides help regulate immune function, activate cell viability, and promote interferon, leukocyte mediators, and tumor necrosis.

Chaga is rich in: superoxide dismutase

Known as a modulator of the immune system, Chaga has the highest levels of superoxide dismutase of any food or herb in the world. Superoxide dismutase is an enzyme that repairs cellular damage, most commonly that of free radicals in the body. Superoxide dismutase, found in the human dermis and epidermis, is key to building skin cell production. In lowering blood sugar, superoxide dismutase can reduce the damage of free radicals to the pancreas. In dealing with cardiovascular diseases, superoxide dismutase can scavenge free radicals in the body, remove stains, and reduce cholesterol and triglycerides.Betulinic acid cost -ZHENYIBIO

Main components of Chaga: Inonotus

Chaga, scientific name Inonotus obliquus, is parasitic on birch trees and continuously absorbs the essence of birch trees to grow. Inonotinol is a lanolin-type triterpenoid, which has high content and strong activity in Inonotus obliquus, and is the iconic component of Chaga. The main chemical components in Chaga mushrooms include sterols, and Inonotus obliquus accounts for about 25-36% of the sterols. Inonotinol obliquus exhibited strong tumor cell inhibition in in vitro experiments on Wacker carcinosarcoma W256 cells and human MCF-7 breast cancer cells and in vivo experiments on leukemia P388 cells in tumor-bearing mice Activity to P388 leukemia tumor-bearing mice intraperitoneally injected with 10 mg/kg of Inonotinol can significantly prolong the survival time of mice. And at a concentration of 50Lg/mL, Inonotinol can kill 100% of W256 carcinosarcoma cells and human MCF-7 breast cancer cells.

The main components of Chaga fungi: triterpenoids

Triterpenoids can effectively inhibit angiotensin-converting enzyme, regulate blood lipids, analgesia, detoxification, anti-allergy, improve blood oxygen supply, regulate blood pressure, prevent and treat hypertension and its complications, and also relieve spasm. When the concentration of triterpenoids reaches 50μg/mL, it can directly kill cancer cells, effectively activate the immune system, and inhibit the special effect of viruses.

Chaga is rich in: betulinic acid

Betulinic acid is a natural pentacyclic triterpenoid found in Chaga mushrooms. Betulinic acid has antitumor, antiviral, and anti-inflammatory activities, among which it is known for its anticancer activity. Studies have found that betulinic acid can induce apoptosis of cancer cells, inhibit tumor growth and resist angiogenesis, and has a selective poisoning effect between normal cells and cancer cells, and has a wide range of inhibitory effects on various cells, showing its Potential in cancer therapy.

Application in cosmetics

Betulinic acid has the effect of whitening the skin. Low-concentration betulinic acid can be used as a skin conditioning aid. It can be used together with ascorbic acid to promote the formation of cortical collagen; it can be used in hair products to promote hair growth; it can eliminate free radical DMBA and other data Said that betulinic acid has anti-inflammatory and anti-allergic effects, and can reduce skin irritation when used in high SPF sunscreen lotions.