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How to use 4-butylresorcinol in cosmetic formulation?

Views: 22     Author: Site Editor     Publish Time: 2023-01-04      Origin: Site

Whitening and freckle removal, a skin care problem that causes headaches for beauty lovers, has a huge rigid demand in the beauty industry market. In addition to skin care products that focus on freckle removal and whitening, you should also understand the functional king fried ingredients in the formula list.

What I want to introduce to you today is 4-butylresorcinol, which fights against the growth of spots and has outstanding whitening effects. As the core whitening ingredient in the skin care industry, 4-butylresorcinol plays an excellent role in skin care.

The whitening and anti-freckle principle contained in 4-butylresorcinol mainly lies in slowing down the production rate of melanocytes. With its small size, it is easier to penetrate into the bottom of the muscle, inhibit the activity of tyrosinase, and prevent the production of melanin.

Compared with the situation that the highest addition ratio of 4-butyl resorcinol in the market does not exceed 0.7%, the 1.5% stable ratio of whitening and freckle cream is also the highest standard ingredient addition that can be achieved in the beauty industry market.butylresorcinol factory

As a miraculous whitening active substance, like 377, it is also a derivative of resorcinol, which has been clinically proven to have freckle-removing and whitening effects, and traces of it can be found in many skin care products.

4-Butylresorcinol performed far better than conventional whitening ingredients such as "kojic acid and arbutin" in the test of "inhibiting tyrosinase activity" in vitro.

In theory, 0.1% can be effective. Therefore, the conventional concentration of products on the market is below 0.5%.

4-Butylresorcinol can not only directly inhibit the activity of tyrosinase, but also simultaneously inhibit tyrosinase-related protein-1 (TRP-1), (it can catalyze the melanin-mediated 5, 6-dihydroxy Oxidation of indole-2-carbolylic acid (5, 6-dihydroxyindole-2-carbolylic acid).

Clinical studies have also confirmed that 4-butyl resorcinol has the effect of significantly reducing pigmentation, which is significantly better than methyl resorcinol and phenylethyl resorcinol 377 (0.3% 4-butyl resorcinol was used in the test The preparation of 1-methylresorcinol with 0.3% hexylresorcinol and 0.5% phenethylresorcinol improved pigmentation.

To sum up: the whitening effect of 4-butyl resorcinol is very powerful‼ ️ Compared with other resorcinol derivatives, butyl resorcinol and 377 (phenylethyl resorcinol) and hexyl resorcinol are significantly better than these two derivatives in lightening spots‼ ️ ️

Generally speaking, if it is tolerant skin, treatment with brush acid or anti-bacterial and anti-inflammatory ingredients can be relieved to a large extent, such as fruit acid (AHA), salicylic acid (BHA), benzoyl peroxide (PBO) or some antibiotics, etc., but if you have sensitive skin, then these relatively irritating ingredients are not suitable, often the acne is eliminated, but the skin is more traumatized, leaving many sequelae.

4-Butylresorcinol is a high-efficiency skin whitening and brightening agent, which has the following effects:

1. Strong inhibitor of 4-butylresorcinol to tyrosinase and peroxidase;

2. 4-Butylresorcinol is an effective skin whitening agent and toner for normal skin;

3. 4-Butylresorcinol is an effective whitening agent for pigmented skin;

4. 4-Butylresorcinol can effectively fight against melasma (excessive pigmentation of skin exposed to sunlight);

5. 4-Butylresorcinol has a strong protective effect on DNA damage induced by H2O2;

6. 4-Butylresorcinol proved to have anti-glycation effect.

In the three processes of melanin source synthesis, 4-butylresorcinol not only has an important inhibitory effect on tyrosinase activity, but also has a synergistic effect on its whitening activity in the process.

1 Before the synthesis of melanin, it interferes with the synthesis and glycosylation of tyrosinase to prevent the enzyme from being absorbed by melanosomes.

2 During melanin synthesis, it inhibits the activity of enzymes, acts as a competitive inhibitor of tyrosinase and TRP1 enzymes, and reduces the formation of by-products that promote melanin production.

3 After melanin is synthesized, it improves the degradation of tyrosinase, inhibits the transfer of melanosomes to keratinocytes, and has a light stripping effect due to the action of fatty acids. This function is enhanced by the presence of fatty acids and regulates tyrosinase degradation.


Creams, essences, essential oil systems.

Addition amount: 0.1-0.3%