What is 4-butylresorcinol?

In the rivers and lakes of whitening ingredients, there are many famous whitening ingredients.

Niacinamide, arbutin, tranexamic acid, glabridin, resveratrol, phloretin, ferulic acid, tetrahydrocurcumin, vitamin C and its derivatives (VC ethyl ether, VC sodium phosphate, VC magnesium phosphate, VC ethyl ether, AA2G, VC-IP, etc.), kojic acid, 377, UP302 (dimethoxycresyl-4-propylresorcinol), etc., in fact, there are many more.

Among these whitening ingredients, some ingredients sell well, but the effect is not very satisfactory (the operation is as fierce as a tiger, and the dark complexion remains the same); some strong drug ingredients (resorcinol derivatives, fruit acids, etc.) are very effective Good, but the irritation is not small, and even the risk of bad face due to misoperation is daunting; of course, there are some effective but notorious banned ingredients (glucocorticoids, aminomercuric chloride, etc.).

For example, Niacinamide has been deified to have innumerable functions (acne removal, oil control, shrink pores, lighten acne marks, sun protection, anti-oxidation, whitening, etc.), plus the formula is easy to use, water-soluble and does not change color, and it is easy to carry Ready to use, deeply loved by formulators;

With the popularity of "nicotinamide stock solution", the addition of various versions of niacinamide stock solution has increased from 2% to 10%, creating a "sales myth" that cannot be matched by other whitening ingredients.

Know the way of whitening

Before introducing 4-butylresorcinol, it is necessary to insert the whitening approach, that is: when developing the formula of whitening cosmetics, what tricks can reduce melanin.

During the research and development of whitening formulas, the main whitening approaches to be considered are mainly 5 directions,

1. Defense against ultraviolet rays: ultraviolet rays are the most critical factor causing pigmentation; if you want to whiten, you must first protect yourself from sun protection;

2. Intracellular inhibition of melanocytes (in which the intracellular pathways can be subdivided into at least 9 small pathways): it is to do everything possible to reduce the efficiency of the melanin synthesis factory of "melanocytes", and the amount of melanin synthesis is reduced. possible real whitening;

3. Extracellular inhibition of melanocytes: Basically, various cell signals (actually the "distress signal" sent by epidermal cells after being irradiated by ultraviolet rays) cannot be transmitted to melanocytes, there is no order, and the factory (melanocytes) naturally If there is no output, it will be white;

4. Inhibit the transshipment of melanin: better understand, it is to prevent the produced product (melanin) from being smoothly and normally delivered to major stores (epidermal keratinocytes);

5. Promoting the renewal of the stratum corneum: Various means to accelerate the consumption of stores (epidermal) inventory (melanin), fruit acids (lactic acid, glycolic acid, lactobionic acid, mandelic acid, etc.), exfoliation, papain, etc. are common method.

The whitening principle embodied by 4-Butylresorcinol (4-Butylresorcinol) mainly focuses on the second major pathway of intracellular inhibition of melanocytes. In addition, because of its petite body, it is easy to penetrate into the skin and penetrate into tyramine Active center of acidase, exerts strong inhibitory activity.

Friends who often pay attention to whitening products should be more familiar with 377 (phenylethylresorcinol), which has been very popular in recent years. In fact, the components of the resorcinol family (4-butylresorcinol, hexylresorcinol, Phenylethylresorcinol, dimethoxycresyl-4-propylresorcinol, glabridin, etc.), are "powerful head whitening ingredients" that inhibit tyrosinase activity.

4-Butylresorcinol can snatch the title of "the second strongest on the earth's surface", mainly because of its super powerful inhibition of tyrosinase activity.

Among these powerful head whitening ingredients, 4-butylresorcinol will be slightly better.

Friends who often pay attention to whitening products should be more familiar with 377 (phenylethylresorcinol), which has been very popular in recent years. In fact, the components of the resorcinol family (4-butylresorcinol, hexylresorcinol, Phenylethylresorcinol, dimethoxycresyl-4-propylresorcinol, glabridin, etc.), are "powerful head whitening ingredients" that inhibit tyrosinase activity.

4-Butylresorcinol can snatch the title of "the second strongest on the earth's surface", mainly because of its super powerful inhibition of tyrosinase activity.

Among these powerful head whitening ingredients, 4-butylresorcinol will be slightly better.

After all, there is still a certain gap between cell experiments and clinical applications, so the research team also organized clinical tests with 14 elderly volunteers (55-60 years old, female). Age spots were treated twice a day with a formulation containing 0.3% 4-butylresorcinol, 0.3% hexylresorcinol and 0.5% phenethylresorcinol.

After 8 weeks, 4-butylresorcinol significantly reduced age spots, significantly better than hexylresorcinol and phenylethylresorcinol.

Finally, here is an example of the effect of our internal laboratory test. Using 2% 4-butylresorcinol whitening cream, once in the morning and evening for 45 days, the effect is really amazing, and the skin tone is significantly improved every week. Changes, and even a few age spots have gradually faded, leaving only a faint mark.