Glabridin: Licorice Root Extract for Skin Whitening

Glabridin is a flavonoid active ingredient derived from licorice root.It is a common whitening ingredient.Only 1 gram of glabridin can be extracted from every 500 kg of licorice root.Its whitening effect is 1000 times that of vitamin C, so it also enjoys the reputation of "whitening gold".As the main ingredient of licorice skin, glabridin is mild and non-irritating.Glabridin is recognized as a safe and scientific whitening cosmetic ingredient.

1.Glabridin Benefits in Cosmetics

Whitening:

Plamed uses the latest technology to develop PCR water-soluble glabridin, whose bioavailability is three times that of ordinary glabridin, which reduces the cost of glabridin by one-third. Glycyrrhiza glabra can penetrate deep into the inner layer of the skin to exert a high-efficiency whitening effect. Effectively inhibit the activity of various enzymes in the process of melanin production, especially the activity of tyrosinase.Glabridin also has anti-rough, anti-inflammatory and antibacterial effects.Glabridin is a recognized whitening ingredient with good curative effect and comprehensive functions.

2.Glabridin Cosmetics Application 

In 1989, Japan's MARUZEN company first used glabridin as a whitening additive.After years of practice, its role is becoming more and more obvious.Licorice root is safe for skin lightening.Glabridin has become a popular whitening ingredient in international high-end cosmetics.This ingredient is widely used in cosmetic brands in Japan, South Korea, Europe and the United States, such as Whoo, Estee Lauder, Lancome, Dior, Sonia Rykiel, Chanel, etc.

3.Glabridin effect

In an experiment conducted by the effect of licorice powder on skin whitening and anti-inflammation was verified.At the same time, the relationship between the structure of glabridin and its curative effect was also studied.

Whitening:

The experiment uses ultraviolet light to irradiate the brown backs of guinea pigs.Then apply 0.5% licorice to the pig's back.The results showed that glabridin can significantly reduce hyperpigmentation caused by UV rays.At the same time, 0.1% dopa was applied to the skin tissue of the same part; then the number of dopa-positive melanocytes per square millimeter was calculated by optical microscope.Therefore, the ability of glabridin to inhibit melanin formation was estimated.According to the skin tissue study, it was found that the dopa-positive melanocytes decreased in the drug treatment group.Glabridin can also whiten the skin.Therefore, the researchers concluded that licorice root extract can inhibit the formation of melanin.

Anti-inflammation

Guinea pigs were exposed to ultraviolet light to cause hyperpigmentation;then 0.5% licorice powder solution (glabridin) was applied. Glabridin was found to reduce skin inflammation caused by UV exposure.The researchers also investigated the activity of glabridin in inhibiting cyclooxygenase.Cyclooxygenase is an enzyme that converts arachidonic acid into prostaglandins.Prostaglandins are pro-inflammatory factors.The experimental results showed that glabridin inhibited the production of arachidonic acid by inhibiting cyclooxygenase.Thus it reduces inflammation..