★What is the appearance and purity of your Glabridin?
Our Glabridin is white or off-white crystalline powder, with three purity grades available: 40% (cosmetic entry-level), 90% (cost-effective), 99% (high-end). All products are detected by HPLC, with low impurity, no color interference in formulations, and stable batch consistency.
★Is Glabridin water-soluble or oil-soluble? How to dissolve it in formulations?
Glabridin is lipophilic (oil-soluble) (Log P≈3.5), insoluble in pure water. It can be pre-dissolved in ethanol, propylene glycol, 1,3-butanediol or other organic solvents (recommended ratio 1:5) before adding to oil phase or emulsified formulations, which can significantly improve solubility and compatibility.
★What is the CAS number and source of Glabridin?
The CAS number of Glabridin is 59870-68-7, EINECS number: 611-908-7 (available for global customs clearance and product registration). Our Glabridin is extracted from wild-simulated Glycyrrhiza glabra in Xinjiang, China, with no pesticide residues, zero irrigation, and 100% natural raw materials.
★What skincare products is Glabridin suitable for?
Glabridin is widely used in high-end cosmetic formulations, including: whitening serums, spot-correcting creams, brightening essences, soothing lotions, post-sun repair products, anti-aging creams, eye creams, firming masks and sensitive skin care products.
★What is the recommended concentration of Glabridin in formulations?
The recommended addition concentration varies according to purity grades:
- 40% purity: 0.5%–2% (suitable for entry-level whitening products)
- 90% purity: 0.1%–1% (cost-effective, suitable for mainstream whitening and soothing products)
- 99% purity: 0.05%–0.5% (high-end, suitable for high-end anti-aging and sensitive skin products)
It can be adjusted according to product positioning and efficacy requirements.
★What pH range is suitable for Glabridin?
Glabridin is stable and effective in pH 5.0–7.0 (weakly acidic to neutral environment). Alkaline environment (pH>7.5) will accelerate its degradation and reduce its activity, so it is not recommended to use it in alkaline formulations.
★What ingredients can Glabridin be compounded with? (Glabridin compatible ingredients)
Glabridin has good compatibility, and can be compounded with the following ingredients to enhance efficacy:
- Whitening ingredients: Niacinamide, Arbutin, Tranexamic acid, VC derivatives (MAP, SAP, 3-O-Ethyl Ascorbic Acid)
- Soothing ingredients: Ceramide, Hyaluronic acid, Panthenol, Centella asiatica extract
- Anti-aging ingredients: Peptides, Retinol (low concentration), Collagen
It is not recommended to compound with strong acid ingredients (pH<4.0) to avoid reducing activity.
★How does Glabridin compare to Kojic Acid, Arbutin, and Vitamin C?
Glabridin is one of the most potent natural whitening agents. On a molar basis, its tyrosinase inhibition activity is 10-15x stronger than kojic acid and 30-50x stronger than arbutin. Unlike vitamin C, Glabridin is stable and does not oxidize. However, it is oil-soluble (not water-soluble) and significantly more expensive. It also provides anti-inflammatory benefits that most other whitening agents lack.
★What is the recommended dosage of Glabridin in skin care products?
Due to its high potency, only 0.1-1.0% is typically used.
Brightening serums / essences: 0.2-0.5%
Anti-spot creams / lotions: 0.3-1.0%
Daily moisturizers / toners: 0.1-0.3%
Anti-inflammatory / calming products: 0.1-0.2%
Even at 0.1%, Glabridin shows significant tyrosinase inhibition. At 0.5%, it is comparable to 2-3% kojic acid in efficacy but with much better skin tolerance.
★Is Glabridin approved for cosmetic use in the EU, USA, and China?
EU: Listed in CosIng as Glabridin (CAS 59870-68-7) with no concentration restriction.
USA: Allowed; FDA has no specific ban. It is also GRAS for certain food uses.
China (NMPA): Listed in IECIC 2021 (INCI: 光甘草定) with no maximum concentration specified (typical use ≤1%).
We provide full registration documents including COA, MSDS, TDS, and China compliance declaration.
★Is Glabridin natural? Does it come from licorice?
Yes, our Glabridin is derived from Glycyrrhiza glabra (licorice) root through a green extraction and purification process. It is 100% natural, non-GMO, and contains no synthetic additives. However, note that natural Glabridin is expensive and limited in supply. We also offer synthetic or bio-identical Glabridin at a lower cost – please ask for details. All grades are vegan and free from animal-derived ingredients.
