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Ascorbyl Tetraisopalmitate

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Other Name: tetrahexyldecyl ascorbate serum; Tetrahexyldecyl Ascorbate
INCI Name: TETRAHEXYLDECYL ASCORBATE
Molecular Formula: C70H128O10
Molecular Weight: 1129.76
Appearance: Colorless to light yellow liquid
Purity: 98%
CAS NO.: 183476-82-6
EINECS No.: 201-081-7
Availability:

Ascorbyl Tetraisopalmitate Serum Powder

Ascorbyl Tetraisopalmitate is a highly stable and oil-soluble derivative of vitamin C. It is often used in skincare products due to its ability to penetrate the skin easily and deliver the benefits of vitamin C. This ingredient has antioxidant properties that help protect the skin against free radical damage, promote collagen production, and brighten the complexion. Additionally, Ascorbyl Tetraisopalmitate may help to reduce the appearance of fine lines, wrinkles, and hyperpigmentation. Overall, it is a popular ingredient in skincare formulations for its potential anti-aging and skin-brightening effects.



The Efficacy of Ascorbic Acid Tetraisopalmitate


High magnification penetration and targeted delivery; High stability, non degradable and non discoloring water-soluble VCIP; The total skin retention is 7.7 times that of regular products; The target active epidermal content is 19.3 times higher than that of ordinary products; Excellent whitening and brightening effects, restoring youthful radiance to the skin; After 28 days of clinical practice, RESEAR can effectively reduce the average value of pigmentation by 12.38%. It can be directly compounded in various cosmetics such as cream, lotion, essence, spray facial mask or gel.

COA of Ascorbyl Tetraisopalmitate

★What is the appearance and purity of your Tetrahexyldecyl Ascorbate?

Our Tetrahexyldecyl Ascorbate is colorless to pale yellow transparent oily liquid, with purity ≥ 98% (HPLC detection). It has no obvious odor, good fluidity, and stable batch consistency, which will not affect the color of the formula.


★Is Tetrahexyldecyl Ascorbate water-soluble or oil-soluble? How to dissolve it in formulations?

Tetrahexyldecyl Ascorbate is oil-soluble (Log P≈8.5), insoluble in pure water, and can be directly dissolved in oil phase, emollients (such as jojoba oil, squalane) and lipid solvents. It has excellent compatibility with oil-based and emulsified formulations, and no pre-dissolution is required.


★What skincare and color cosmetic products is Tetrahexyldecyl Ascorbate suitable for?

It is widely used in high-end cosmetic formulations, including: whitening serums, anti-aging creams, firming lotions, facial oils, sunscreens, post-sun repair products, eye creams, foundation, concealer and other products. It is especially suitable for oil-based and emulsified formulations.


★What is the recommended concentration of Tetrahexyldecyl Ascorbate in formulations?

The recommended addition concentration is 0.5%–5%, which can be adjusted according to product positioning:

- 0.5%–1%: Suitable for daily maintenance, mild brightening and anti-oxidation.

- 1%–3%: Suitable for mainstream whitening and anti-aging products, with obvious effect.

- 3%–5%: Suitable for high-end spot-lightening and intensive anti-aging products, with strong efficacy.


★What pH range is suitable for Tetrahexyldecyl Ascorbate?

Tetrahexyldecyl Ascorbate is stable and effective in pH 5.0–8.0 (weakly acidic to neutral environment). It has good stability in both acidic and neutral formulations, and will not degrade or lose activity, which is suitable for most cosmetic formulations.


★Is VC-IP approved for cosmetic use in the EU, USA, and China?

EU: Listed in CosIng as Ascorbyl Tetraisopalmitate (CAS 183476-82-6) with no concentration restriction.

USA: Allowed; FDA has no specific ban.

China (NMPA): Listed in IECIC 2021 (INCI: 抗坏血酸四异棕榈酸酯) with no maximum concentration specified. Typical use ≤5%.

We provide full registration documents including COA, MSDS, TDS, and China compliance declaration.


★Can VC-IP be combined with other active ingredients (retinol, niacinamide, peptides, AHAs)?

Yes, VC-IP is highly compatible with most cosmetic actives:

With retinol: Excellent synergy for anti-aging. Both are oil-soluble and stable.

With niacinamide: Can be combined in emulsions (oil-soluble VC-IP in oil phase, niacinamide in water phase).

With peptides: Fully compatible.

With AHAs/BHAs: Yes, but keep pH >4.0 if using high concentrations of acids (though VC-IP itself is stable down to pH 4.0).

With sunscreen agents: VC-IP acts as an antioxidant booster, reducing UV damage.

Avoid combining with strong oxidizing agents (e.g., high-concentration benzoyl peroxide) in the same formula.


★What is the difference between Tetrahexyldecyl Ascorbate and pure VC? (THD Ascorbate vs pure VC)

- Tetrahexyldecyl Ascorbate: Oil-soluble, high stability, no oxidation and discoloration, good skin permeability, mild, no irritation, long-lasting effect.

- Pure VC (L-Ascorbic Acid): Water-soluble, poor stability, easy to oxidize and yellow, poor skin permeability, obvious irritation, short effect duration.

Tetrahexyldecyl Ascorbate solves the defects of pure VC and is more suitable for long-term use.


★Why is Tetrahexyldecyl Ascorbate suitable for high-end cosmetics?

Its high-end positioning is mainly due to three advantages:

- High stability and activity: It is not easy to oxidize, and can retain efficacy for a long time;

- Good skin permeability: It can penetrate the skin deeply and exert effect, with obvious effect;

- Mild and safe: It has no irritation, is suitable for all skin types, and can meet the high requirements of high-end cosmetics for safety and efficacy.