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Glycyrrhetinic Acid

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Other Name: Carbenoxolone
INCI Name: GLYCYRRHETINIC ACID
Molecular Formula: C30H46O4
Molecular Weight: 470.68
Appearance: White crystalline powder
Purity: 98%
CAS Number: 471-53-4
EINECS number: 207-444-6
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Carbenoxolone (CBX) is a glycyrrhetinic acid derivative with a steroid structure similar to what found in the roots of licorice plants.Carbenoxolone sodium is used to treat peptic, esophageal and oral ulcers and inflammation.Glycyrrhetinic Acid has also been used in topical creams that treating lip sores and oral ulcers.Licorice extract(beta glycyrrhetinic acid) is used in the field of cosmetics. Licorice extract(18 beta glycyrrhetinic acid) can nourish and heal the skin.

Specification
Standard
Appearance
White or almost white crystalline powder
Solubility
Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride, it shows polymophism
IR or TLC and coloured reaction
Positive
Appearance of solution
The solution is clear and not more than intensely coloured than reference solution Y6
Specific optional rotation
+145°~ +154°
Any impurity
≤0.7%
Total impurity
≤2.0%
Loss on drying
≤0.50%
Heavy metals
≤10ppm
Sulphated Ash
≤2.0%
Assay (by potentiometry,
on dried substance)
98.0-101.0%


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