Phloretin is a dihydrochalcone, a natural phenol. It can be found in apple tree leaves[1] and manchurian apricots. [2]metabolism[edit]In rats, ingested phloretin is converted to phloretin by hydrolytic enzymes in the small intestine. [3][4] Phloretin hydrolase hydrolyzes phloretin into phloretin and