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Tretinoin

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Other Name: Retinoic acid;VITAMIN A ACID
INCI Name: RETINOIC ACID
Molecular Formula: C20H28O2
Molecular Weight: 300.44
Appearance: Yellow powder
Purity: 98%
CAS Number: 302-79-4
EINECS number: 206-129-0
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tretinoin vitamin a acid powder manufacturer-zhenyibio


Retinoic acid (Tretinoin) is a derivative of vitamin A.So it also been called Vitamin A acid(Retin-A).Retinoic Acid can be used on the skin (topical) to treat moderate to moderate acne, as well as on skin that has been damaged by excessive exposure to the sun.Tretinoin powder can be used for removing moderate acne,wrinkles and spots in the skin.


Tretinoin may bring the following benefits:Reduce the appearance of fine lines and dark spots; Improve skin texture;Reduce the frequency and severity of acne outbreaks;Clean up existing acne.


Benefits of Tretinoin

1.proliferation can be promoted in normal epidermis, but it can be normalized in hyperproliferative epidermis.

2.The effect on sebaceous gland activity and epidermal lipids. Retinoic acid can prolong the maturation process of basal cells, reduce the number of sebaceous gland cells, reduce sebum synthesis, and reduce sebum secretion rate accordingly. At the same time, tretinoin can also change the lipid composition in the sebaceous glands, thereby inhibiting the reproduction of Propionibacterium acnes.

3.Immune regulation and anti-inflammatory effects. Usually stimulates humoral and cellular immunity, but immunosuppression has also been reported. Its anti-inflammatory effect is mainly achieved by regulating neutrophil chemotaxis.

4.Reduce epidermal melanin. Reduces melanin formation by reducing melanosome input into keratinocytes and inhibiting tyrosinase activity.

5.Tretinoin products can also interfere with the occurrence of tumors and exert anti-tumor activity. Therefore, tretinoin products can be used for acne, psoriasis (psoriasis), ichthyosis, follicular keratosis, etc. Abnormal-related skin diseases can also be used to prevent and eliminate tumors and skin aging.

Retinoic acid to remove acne can directly or indirectly act on 4 main links in the pathogenesis of acne: inhibition of sebaceous gland function; anti-keratinization of hair follicles and sebaceous ducts; inhibition of microbial growth in hair follicles and sebaceous ducts; inhibition of inflammation.


Reference dosage: Cold cream ointment below 0.025% is used to treat acne and facial roughness. 0.1% cold cream ointment is used to treat lichen planus, pityriasis rubra, vitiligo and other skin diseases.

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