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Calcium Alpha-Ketoglutarate (Ca-AKG) is a stable salt form of the vital metabolic intermediate alpha-ketoglutarate, a key molecule in the Krebs cycle. At ZHENYIBIO, our specialized factory utilizes high-precision crystallization and stabilization technologies to produce premium Ca-AKG powder with a purity of 98\%. Recognized as a breakthrough in longevity science, Ca-AKG helps support cellular energy production and may delay age-related physiological decline. As professional manufacturers, we ensure our Calcium AKG is highly stable, making it ideal for supplement manufacturers who require a non-hygroscopic ingredient for capsules and tablets. As one of the most reliable suppliers in China, ZHENYIBIO provides consistent batch quality and full technical documentation (COA, MSDS) to meet international regulatory standards. By sourcing directly from our factory, you benefit from competitive wholesale prices and a transparent supply chain.
Benefits of Calcium alpha Ketoglutarate
Healthy Aging & Longevity: Supports cellular rejuvenation and DNA repair, helping to extend biological "healthspan."
Mitochondrial Function: Acts as a crucial fuel for the Krebs cycle, boosting overall cellular energy (ATP) production.
Muscle & Bone Health: Supports protein synthesis and may help maintain bone density in aging populations.
Metabolic Support: Helps manage nitrogen balance and supports healthy kidney and liver function.
Applications of Calcium alpha Ketoglutarate
Dietary Supplements: The core ingredient for anti-aging capsules, longevity formulas, and vitality blends.
Sports Nutrition: Used in recovery formulations to support muscle repair and metabolic efficiency.
Clinical Nutrition: Targeted at supporting nitrogen metabolism and age-related health management.
★What is Calcium Alpha-Ketoglutarate (Ca-AKG)?
Calcium Alpha-Ketoglutarate (Ca-AKG) is a calcium salt form of alpha-ketoglutarate, a key molecule in the Krebs cycle. It is highly valued in the longevity industry for its ability to support metabolic health and cellular energy production.
★Why is Ca-AKG preferred over regular Alpha-Ketoglutarate?
Ca-AKG is more stable and has a slower release profile in the bloodstream compared to the acid form. It also provides a supplemental source of calcium and is less prone to moisture absorption, making it ideal for capsules and tablets.
★How does Ca-AKG promote longevity and anti-aging?
Research indicates that Ca-AKG can reduce systemic inflammation (inflammaging) and help maintain DNA methylation patterns, potentially slowing biological aging and extending a healthy lifespan.
★Can Ca-AKG be used alongside NMN or Resveratrol?
Ca-AKG is often stacked with NMN (Nicotinamide Mononucleotide) and Resveratrol. While NMN boosts NAD+ levels, Ca-AKG supports the metabolic pathways that utilize that energy, creating a synergistic anti-aging effect.
★Does Calcium Alpha-Ketoglutarate support bone health?
Yes. Beyond its metabolic benefits, the calcium component in Ca-AKG contributes to bone density, while the alpha-ketoglutarate part promotes collagen synthesis, which is essential for bone matrix and skin elasticity.
★Is your Ca-AKG powder soluble in water?
Ca-AKG has moderate solubility in water. It dissolves more slowly than the pure acid form but is stable once in solution, making it suitable for functional drinks or powdered mixes.
★Is Calcium Alpha-Ketoglutarate safe and are there any side effects?
Ca-AKG is generally considered safe (GRAS). It is a substance naturally found in the human body. Side effects are rare but may include mild digestive upset if taken in excessive amounts.
★Is your Ca-AKG derived from natural sources?
Our Ca-AKG is produced through advanced fermentation or high-purity synthesis processes that ensure it is bio-identical to the AKG found in the human body, and it is 100% Vegan and Non-GMO.
★Do you provide COA and HPLC testing for every batch?
Absolutely. As a professional supplier, every batch of our Calcium Alpha-Ketoglutarate undergoes rigorous quality control. We provide COA, MSDS, and HPLC reports to guarantee a purity of ≥98%.