Views: 3 Author: Site Editor Publish Time: 2022-10-03 Origin: Site
What is peptide?
Peptides, also known as peptides or polypeptides, are small molecules of protein.
Compared with macromolecules, the biggest difference between small molecules is their small molecular weight and biological activity, most of which can be directly absorbed by the human body without further decomposition, which greatly improves the absorption efficiency.
For our human body, protein is the most important structural component in addition to DNA and RNA. A large number of proteins exist in various important organs and tissues.
If we take a sharp knife and completely split the protein, we will find that no matter what kind of protein it is, it is composed of more than 20 amino acids in different proportions, and if the knife is not sharp enough or we do not It's handy, just split the protein into pieces, then this piece of stuff is called a polypeptide.
From a scientific and rigorous academic point of view, polypeptides with more than 20 amino acids are called polypeptides, and those with less than 20 amino acids are called oligopeptides. However, in the application of ingredients in skin care products, there is no such strict subdivision.
The name of the peptide is defined according to the number of amino acids it contains, such as 2 amino acids to form a dipeptide, 3 amino acids to form a tripeptide, and so on. So the three peptides and five peptides we often hear come from this way, do you finally know why?
According to the above naming, we know that there are many kinds of peptides, but because each type of peptide contains different types of amino acids, so the functions are not the same. Although we know through various publicity channels that peptides can be used in skin care products for anti-aging.
What is the role of peptides?
1. By inhibiting the synthesis of SNARE and the excessive release of catecholamine and acetylcholine in the skin, it can locally prevent nerves from transmitting muscle contraction information, promote facial muscle relaxation, and reduce wrinkles.
The peptides with such effect are: two peptides, five peptides and so on.
2. Promote the synthesis of basic protein, increase the proliferation of collagen, elastic fibers and hyaluronic acid, improve the moisture content of the skin, anti-wrinkle and firm the skin.
Peptides with such effects include: hexapeptides and the like.
3. Improve skin edema, improve microcirculation, strengthen blood circulation, and eliminate inflammation.
Peptides with such effects include: tetrapeptides and the like.
4. Anti-carbonylation, protect collagen from being damaged by active carbonyl groups, scavenge free radicals, and promote collagen growth; in addition, it also helps skin resist oxidation and glycation.
The peptides with such effect are: tripeptide and so on.
5. Block the conduction of melanin, inhibit the activity of tyrosinase, and reduce the chance of melanin production.
Peptides with such effects include: nine peptides and the like.
Among these peptides, the most famous one should be the blue copper peptide. In addition to its intoxicating blue color, its noble price also makes it unique and its reputation is far ahead.
In the 1970s, American Dr. Loren Pickart discovered a naturally occurring plasma peptide in serum when he was studying why the liver tissue of the elderly could still synthesize new proteins.
Further research found that it is a complex structure formed by the combination of a polypeptide (tripeptide-1) composed of glycyl-L-histidyl-L-lysine and copper ions.
It is centered on copper ions and surrounded by three amino acid molecules. Because of the copper ions in it, its solution shows a strange blue color, especially like the magic potion in Harry Potter, so it is customary to call it as Blue copper peptide (GHK-CU), also known as blue copper peptide, tripeptide-1 copper.
Blue copper peptide is a small molecule protein and is the earliest discovered peptide. To put it more bluntly, this thing is a combination of a polypeptide (tripeptide-1) and a copper ion. If you leave out this copper ion, the tripeptide-1 is mediocre and basically worthless. What kind of money, the function is relatively general, but because of the combination of a copper ion, it is commendable.
Scientific research institutions have done a lot of in vitro experiments and clinical comparison experiments, and compared with the traditional anti-aging ingredients VC and VA.
The effects of blue copper peptides on the skin can be summarized as: 1. Anti-aging; 2. Promote wound healing and repair damaged skin; 3. Antioxidant.
After the blue copper peptide enters the skin, it releases a signal to induce fibroblasts to produce collagen and promote collagen production. In addition, blue copper peptides can carry copper ions into the cell, and release copper ions after encountering enzymes. Copper ions are very important components in many enzymatic reaction processes.
It can promote the production of proteoglycan (GAG), which is an important component of the extracellular matrix, which can make the skin plump, moisturizing and full of elasticity.
In vitro experiments have shown that its ability to stimulate the synthesis of collagen precursors is stronger than that of anti-aging ingredients such as retinoic acid and vitamin C. Therefore, the anti-aging effect of blue copper peptide is beyond doubt, but the wrinkle-removing effect is not as fast as vitamin A, and it takes several months to feel the effect.
◆ Promote wound healing and repair damaged skin
It can promote the growth, division and differentiation of nerve cells and immune-related cells, effectively promote wound healing, repair damaged skin, inhibit the synthesis of many inflammatory factors, and have anti-inflammatory effects.
This is also the reason why it is recommended to use products containing blue copper peptides as after-care after acne treatment. There are tiny wounds on the skin surface, damaged, sensitive and fragile skin, the use of products containing blue copper peptides has a repairing effect.
The antioxidant effect of blue copper peptide has been confirmed in vitro and animal experiments. It can block the formation of reactive oxygen species, remove various peroxides, protect keratinocytes from UV damage, and block free radical damage to the liver to protect the liver. The excellent antioxidant effect of blue copper peptide can brighten the complexion, refine the skin, and prevent skin aging.
The beauty effects of blue copper peptides have been tested by many scientists, including:
Stimulates the formation of collagen and elastin, firming the skin and reducing fine lines.
Restore skin repair ability, increase the production of intercellular mucilage in the skin, and reduce skin damage.
Stimulate the formation of glucopolyamine, increase skin thickness, reduce loose skin and firm skin.
Promote the proliferation of blood vessels and increase the oxygen supply to the skin.
Auxiliary antioxidant enzyme SOD, has a strong and beneficial anti-free radical function.
As one of the hot ingredients in recent years, blue copper peptides have been published by many dermatologists in clinical human experiment reports, confirming that blue copper peptides can enter the dermis layer of the skin and exert their curative effect. Compared with other peptide ingredients, blue copper peptide can mildly have anti-aging, healing, repairing and other skin care effects on the skin. Other peptides may be irritating or have a single effect. Therefore, blue copper peptide is recommended by dermatologists. Praised as a non-irritating anti-aging and anti-wrinkle ingredient for the 21st century. It is now being used in high-end beauty salon products, luxury brand skin care products, and after medical and cosmetic surgery.
Promote collagen and elastin regeneration: this is one of the most important anti-aging functions of blue copper peptides
Promote wound healing: For damaged wounds, blue copper peptides promote the regeneration of fibroblasts and have long been used in medicine
Anti-inflammatory effect: Blue copper peptide can inhibit the synthesis of many inflammatory factors, which is conducive to cell repair
Helping DNA repair: Blue copper peptides can affect the synthesis of many genes (about 4000), and can repair DNA when it is damaged by ultraviolet rays (in vitro experiments).
After the blue copper peptide enters the skin, it induces fibroblasts to produce collagen, which effectively promotes the metabolism of old waste products and the production of collagen. In addition, blue copper peptides can carry copper ions into the cell, and release copper ions after encountering enzymes. Copper ions are very important components in many enzymatic reaction processes, stimulating the synthesis of glucopolyamine, making the skin plump and firmer, and facial lines. Slowly fades for a youthful-looking complexion.
2. Strong repairing power
Blue copper peptides can promote the production of keratinocytes, increase skin thickness, and help repair damaged skin barriers. Injury and other situations can also reduce inflammation and calm, soothe the skin, enhance the skin cell defense and accelerate cell repair.
3. Antioxidant attack
In terms of antioxidants, blue copper peptide is also a good player. It can block the formation of reactive oxygen species and remove various peroxides. At the same time, it is milder and less irritating than ordinary vitamin C and retinol. Sensitive people can also be applied.