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Nicotinamide Powder

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INCI Name: NIACINAMIDE
Molecular Formula: C6H6N2O
Molecular Weight: 122.12
Appearance: white powder
Purity: 99%
CAS NO.: 98-92-0
EINECS No.: 202-713-4
Availability:

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Nicotinamide, is an amide compound of niacin. A white crystalline powder; Odorless or almost odorless, with a bitter taste; Slightly hygroscopic. Soluble in water or ethanol, soluble in glycerol.


Application


1. Biochemical research: Nicotinamide is a nutritional component of tissue culture medium; The clinical medication is vitamin B, used for the treatment of diseases such as pellagra, stomatitis, and glossitis.


2. Nicotinamide plays multiple roles in cosmetics, mainly including moisturizing and moisturizing, whitening, and brightening skin tone. Niacinamide has antioxidant properties and anti-inflammatory effects, improving skin texture, controlling oil, and shrinking pores. Used in hair care to promote scalp blood circulation, healthy hair follicles, promote hair growth, and prevent baldness.


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★What is the appearance and purity of your cosmetic-grade Nicotinamide Powder?

It appears as white crystalline powder with purity ≥ 99% (HPLC test), low impurity, low nicotinic acid content, and stable batch consistency.


★Is Nicotinamide Powder water-soluble or oil-soluble?

Niacinamide is excellent water-soluble, easy to dissolve in water phase and compatible with most aqueous & emulsified formulas.


★How does Nicotinamide Powder brighten skin?

It inhibits the transfer of melanin from melanocytes to keratinocytes without damaging melanocytes, achieving gentle and long-lasting brightening effect.


★What products is Nicotinamide Powder suitable for?

Whitening serums, oil-control lotions, barrier repair creams, toners, masks, sunscreens, sensitive skin care products and anti-aging cosmetics.


★What is the recommended usage rate of Nicotinamide Powder in formulations?

Daily mild care: 1%–2%

Oil control & brightening: 2%–5%

High-efficiency repair: 5%–10%


★What ingredients can Nicotinamide Powder be compounded with?

It can be combined with vitamin C derivatives, tranexamic acid, arbutin, glabridin, hyaluronic acid, peptides and centella asiatica to enhance efficacy.


★What is the recommended dosage of Niacinamide in cosmetic formulations?

Effective concentration ranges vary by target benefit:

Barrier repair / moisturizing: 2-5%

Skin brightening / hyperpigmentation: 4-5% (studies show 5% effective)

Anti-aging / wrinkle reduction: 3-5%

Sebum control / pore reduction: 2-4%

Anti-acne / anti-inflammatory: 2-5%

General purpose (toners, lotions): 2-3%

Higher concentrations (up to 10%) are safe but may cause mild irritation for some users. For first trials, start at 2-3%. Note: Some markets restrict Niacinamide to ≤5% for leave-on products (check local regulations).


★Is Niacinamide approved for cosmetic use in the EU, USA, and China?

EU: Listed in CosIng with no concentration restriction (typical use ≤5%).

USA: Allowed; FDA considers it safe for cosmetic use.

China (NMPA): Listed in IECIC 2021 (INCI: 烟酰胺) with no maximum concentration specified, but some finished product registration guidelines suggest ≤5% for leave-on.

We provide full registration documents including COA, MSDS, TDS, and China compliance declaration. Note: For export to Japan, Niacinamide is classified as a “quasi-drug” active at certain concentrations; please check local requirements.