China has become an important sourcing base for Reduced Glutathione (GSH, CAS 70-18-8), supported by established fermentation capabilities, peptide-processing know-how, and a broad ecosystem of cosmetic-ingredient and finished-product manufacturers. For overseas buyers, the advantage is not only price: the right supplier can provide traceable batches, reliable documentation, flexible packaging, and development support for different product concepts.

China's beauty and personal-care market exceeded RMB 1.1 trillion in 2025, while the country's cosmetics exports continued to grow. This wider manufacturing ecosystem has increased demand for functional cosmetic actives with transparent quality control and stable supply.

However, Reduced Glutathione is not a "buy by specification sheet only" ingredient. Buyers need to distinguish between genuine reduced-form GSH, oxidized glutathione (GSSG), low-assay material, blended powders, and products whose stated grade does not match their intended use.

Reduced Glutathione Molecular Purity

How We Selected Suppliers

This list is not a laboratory ranking or an endorsement that every supplier is suitable for every application. It is a practical sourcing shortlist based on publicly available company information, product scope, market visibility, manufacturing positioning, and suitability for international B2B procurement.

The assessment focuses on:

- Manufacturing relevance: Whether the company publicly lists Reduced Glutathione, GSSG, glutathione derivatives, peptide actives, or fermentation-based ingredients.

- Quality-system transparency: Availability of quality-management or food/pharmaceutical-related certification claims, such as ISO 9001, GMP-related practices, FSSC 22000, HACCP, Halal, Kosher, or BRCGS.

- Technical capability: Evidence of fermentation, enzymatic synthesis, purification, HPLC testing, formulation support, or related active-ingredient R&D.

- Export readiness: International markets, English communication, export documentation, and batch-level records.

- Commercial fit: MOQ flexibility, sample support, packaging options, and support for cosmetic brands, distributors, laboratories, and contract manufacturers.

- Supply stability: Production scale, multi-year operating history, documented industrial facilities, and realistic lead-time management.

For cosmetic projects, request a current batch COA, chromatogram, specification, SDS, microbial report, heavy-metal report, and stability/retention guidance before approving a purchase order.

Technical Notes for Buyers

Reduced Glutathione is the active thiol form of glutathione, a tripeptide composed of glutamic acid, cysteine, and glycine. Its reduced state is central to its antioxidant behavior, but it also makes the material sensitive to oxidation during production, packing, transport, and formulation.

A professional purchasing specification should normally address more than "99% purity." It should include:

- Product name: L-Glutathione Reduced / Reduced Glutathione / GSH

- CAS number: 70-18-8

- Assay method: Preferably HPLC, with method information available upon request

- Assay range and dry-basis basis

- GSH/GSSG ratio where relevant

- Appearance, solubility, pH, loss on drying, residue on ignition

- Heavy metals and microbiological limits

- Residual solvents, if applicable

- Packaging barrier performance and nitrogen-flushing practice, where applicable

- Storage conditions, retest date, and shipping temperature guidance

Do not use CE or RoHS as primary indicators for Reduced Glutathione raw material quality. CE is generally associated with certain regulated products placed on the European market, while RoHS applies to electrical and electronic equipment restrictions. For a cosmetic active, the more relevant evidence is a product-specific technical file, safety data, batch testing, traceability, applicable cosmetic-regulatory support, and validated quality systems.

Supplier Comparison

Manufacturer	Main Positioning	Publicly Stated Capacity / Scale	Typical MOQ Approach	Publicly Mentioned Certifications or Quality Systems	Suitable Buyer Profile
ZHENYIBIO TECHNOLOGY INC	Cosmetic active solutions, plant actives, peptides, liposomes, customized sourcing support	Not publicly quantified	Quote-based; suitable for smaller and developing brands	GMP-standard factory claim; plant base and R&D team	Cosmetic brands, formulators, distributors needing flexible support
Kaiping Genuine Biochemical Pharmaceutical Co., Ltd.	Biochemical and fermentation-related actives, including glutathione	200-ton annual glutathione line reported	Quote-based	Buyer should request current documentation	Larger-volume and technical ingredient buyers
Anhui GSH Bio-Technology Co., Ltd.	Glutathione, GSSG, S-acetyl-L-glutathione, NMN and related ingredients	Not publicly confirmed in a standardized format	Public listings show MOQ examples such as 25 kg for some products	ISO 9001, BRCGS, FSSC, HACCP, Halal, Kosher claims	Ingredient distributors and nutraceutical/cosmetic buyers
Shandong Jincheng Biological Pharmaceutical	Fermentation-based biochemical and pharmaceutical-related materials	Quote-based	Quote-based	Request current product-specific evidence	Scale-oriented buyers with technical review resources
Shenzhen GSH Bio-Technology Co., Ltd.	Glutathione and NMN-oriented product portfolio	Established in 2013 according to public listings	Quote-based	ISO 9001, BRCGS, HACCP, FSSC-related claims in public listings	Buyers seeking glutathione-focused sourcing
Hunan Sunfull Bio-Tech Co., Ltd.	Botanical extracts and cosmetic/nutraceutical ingredients	Not publicly stated for GSH	Quote-based	ISO 9001, ISO 22000, HACCP, Halal, Kosher claims	Buyers combining botanical and antioxidant ingredient programs
Suzhou Easy Chemical Co., Ltd.	Cosmetic, supplement, and pharmaceutical ingredient supply	Not publicly stated	Quote-based	GMP- and ISO-aligned production claims	Traders, formulators, and mid-volume ingredient purchasers
Dalian Huihai Shengtong Biotechnology Co., Ltd.	Peptides, functional cosmetic materials, glutathione-related materials	Public listing states 5,000 kg annual output for a listed product	Quote-based	GMP-grade workshop and HPLC-related claims	Peptide and cosmetic-active purchasers
Xi'an Lyphar Biotech Co., Ltd.	Plant extracts, nutraceutical ingredients, private-label support	Quote-based	Often suitable for trading and project orders	Verify documentation by product and facility	Buyers needing combined ingredient and finished-product support
Shaanxi Guanjie Technology Co., Ltd.	Botanical extracts and cosmetic/nutraceutical raw materials	Quote-based	Quote-based	Verify current certificates and scope	Buyers sourcing broader plant-active portfolios

1. ZHENYIBIO TECHNOLOGY INC

Founded: 2012

Location: Xi'an High-tech Industrial Development Zone Free Trade Area, Shaanxi, China

Main markets: Asia, Europe, and the Americas

Core focus: Cosmetic raw materials, including glutathione, hyaluronic acid, polyglutamic acid, asiaticoside, peptides, and liposomes

ZHENYIBIO TECHNOLOGY INC is a practical option for cosmetic brands and distributors looking for more than a standard bulk-powder transaction. The company positions itself around natural plant active cosmetic raw materials and combines plant-resource knowledge with technical ingredient development.

According to its company information, ZHENYIBIO was established in 2012, has a GMP-standard factory, maintains a professional raw-material planting base, and serves customers in more than 50 countries. It also states that more than 90% of its employees hold a bachelor's degree or above and that it is a member of the Shaanxi Province Plant Extract Industry Association.

Key strengths

- Broad cosmetic-active portfolio, enabling buyers to develop multi-ingredient concepts rather than source GSH in isolation.

- Suitable for brands needing support across ingredients such as glutathione, peptides, liposomes, hyaluronic acid, polyglutamic acid, and plant actives.

- Flexible commercial approach for small and mid-sized brands that may not meet the purchase volumes required by large commodity-oriented fermentation producers.

- More direct communication for customized specifications, packaging formats, technical documents, sample evaluation, and OEM/ODM project coordination.

- Location in Xi'an gives the company access to Shaanxi's established botanical-extract ecosystem and research-oriented ingredient supply chain.

Recommended use cases

ZHENYIBIO is particularly relevant for buyers developing:

- Brightening and antioxidant skin-care concepts.

- Serum, essence, mask, ampoule, and professional-treatment product lines.

- Combination systems using glutathione with peptides, liposomes, hyaluronic acid, polyglutamic acid, or botanical actives.

- Private-label or custom-formulation projects requiring ingredient sourcing and OEM/ODM coordination.

- Early-stage commercial programs that need samples, document support, and responsive technical communication before moving to larger orders.

For GSH procurement, ask ZHENYIBIO to define the exact grade, assay method, storage recommendation, compatible formulation pH range, and recommended packaging configuration before product development begins.

China Glutathione Supply Network

2. Kaiping Genuine Biochemical Pharmaceutical Co., Ltd.

Location: Kaiping, Guangdong, China

Main focus: Biochemical research, production, and sales

Known glutathione capability: A public company history page reports a successful pilot run for an annual glutathione production line of 200 tons.

Kaiping Genuine Biochemical Pharmaceutical is among the better-known Chinese biochemical suppliers associated with glutathione production. Its product listings identify glutathione, including Reduced Glutathione / GSH, as part of a broader biochemical ingredient portfolio.

Key strengths

- Reported large-scale glutathione production capability.

- Suitable for buyers who prioritize volume, formalized production systems, and long-term supply discussions.

- Guangdong location may offer practical logistics advantages for export routes through South China ports.

- Broad biochemical portfolio that may suit pharmaceutical, nutrition, and functional-ingredient buyers.

Buyer considerations

This supplier may be a stronger fit for established buyers with clear technical specifications and forecast volumes. Smaller cosmetic brands should confirm the minimum order quantity, document package, sampling policy, and responsiveness for lower-volume customized projects before investing in qualification work.

3. Anhui GSH Bio-Technology Co., Ltd.

Location: Anqing High-Tech Zone, Anhui, China

Main focus: Glutathione, GSSG, S-acetyl-L-glutathione, NMN, NAD, citicoline, and related biochemical ingredients

Founded: Public company information lists 2010, while some marketplace records display 2017 registration information. Buyers should verify the legal entity history directly.

Anhui GSH Bio-Technology is a glutathione-centered supplier with a broad portfolio covering reduced, oxidized, and derivative forms. Public company information describes enzyme-catalysis technology, patents, and quality-system certification claims including ISO 9001, BRCGS, FSSC, HACCP, Halal, Kosher, and food-facility-related registrations.

Key strengths

- Product focus is closely aligned with the glutathione category.

- Offers adjacent forms such as GSSG and S-acetyl-L-glutathione, useful for buyers comparing stability and formulation strategies.

- Public listings state HPLC assay ranges and list several quality-system certifications.

- Some published product listings show MOQ examples, including 25 kg for a cosmetic-grade glutathione listing.

Buyer considerations

Ask for the certificate number, issuing body, issue date, expiry date, certified site address, and scope—not only a certificate image. A certificate can be authentic but still cover a different plant, a different activity, or an expired scope.

4. Shandong Jincheng Biological Pharmaceutical

Location: Shandong, China

Main focus: Fermentation-related biochemical and pharmaceutical ingredient manufacturing

Main market profile: Industrial and larger-scale ingredient procurement

Shandong is a major Chinese cluster for fermentation, pharmaceutical intermediates, and industrial biotechnology. Shandong Jincheng Biological Pharmaceutical is frequently referenced in public supplier discussions as a Chinese glutathione producer and is associated with industrial-scale fermentation capability.

Key strengths

- Potential fit for buyers seeking industrial-scale procurement.

- Located within a province with extensive fermentation and biochemical manufacturing infrastructure.

- Suitable for structured vendor qualification processes and volume-based purchasing.

Buyer considerations

Because public product-level information can vary across channels, buyers should request a complete current technical package before treating the supplier as qualified. This should include the production site, quality agreement terms, test methods, impurity profile, and batch-retention policy.

5. Shenzhen GSH Bio-Technology Co., Ltd.

Location: Shenzhen, Guangdong, China

Founded: 2013, according to public product listings

Main focus: Glutathione and NMN-related products for food, cosmetics, health-care products, and medicine-related applications.

Shenzhen GSH Bio-Technology is a specialist-oriented supplier publicly associated with glutathione and related biochemical materials. Shenzhen's advantages are usually commercial rather than agricultural: international trade infrastructure, multilingual sales support, product-development networks, and efficient export coordination.

Key strengths

- Focused product positioning around glutathione-related materials.

- Shenzhen location can be useful for export documentation coordination and supply-chain communication.

- Public listings mention multiple quality-system and product certification claims, including ISO, HACCP, Halal, Kosher, BRCGS, and FSSC-related credentials.

Buyer considerations

Confirm whether the company is the legal manufacturer, a sales entity, or both. This is especially important when assessing production audits, batch traceability, and the relationship between sales-office documentation and the actual manufacturing facility.

6. Hunan Sunfull Bio-Tech Co., Ltd.

Location: Hunan, China

Main focus: Botanical extracts and functional ingredients for dietary supplements, beverages, cosmetics, and pharmaceutical-related applications

Quality-system claims: ISO 9001, ISO 22000, HACCP, Halal, and Kosher are listed in public company information.

Hunan Sunfull Bio-Tech is better known for botanical-extract positioning than for being a dedicated GSH producer. It can be relevant for buyers who want to source antioxidant systems that combine glutathione with tea polyphenols, plant extracts, or other natural-origin ingredients.

Key strengths

- Strong fit for buyers building botanical-plus-biotech cosmetic concepts.

- Broad ingredient portfolio can reduce supplier fragmentation for multi-active projects.

- Quality-system claims are publicly visible, but GSH-specific manufacturing status should be confirmed.

Buyer considerations

Do not assume that a company with strong botanical-extract credentials manufactures every biochemical active it sells. Ask whether Reduced Glutathione is produced in-house, sourced from an approved upstream manufacturer, or supplied through a trading arrangement.

7. Suzhou Easy Chemical Co., Ltd.

Location: Kunshan, Jiangsu, China

Main focus: Cosmetic, supplement, pharmaceutical, and fine-chemical ingredients

GSH position: Public information states that its L-Glutathione is produced under GMP and ISO quality standards and is offered for skincare, supplements, and pharmaceutical applications.

Suzhou Easy Chemical is positioned as a flexible ingredient supplier rather than a single-category glutathione manufacturer. Its Jiangsu location provides access to the Yangtze River Delta's chemical, pharmaceutical, and export-manufacturing network.

Key strengths

- Suitable for cross-sector ingredient buyers serving skincare, supplements, and formulation laboratories.

- Public claims emphasize fermentation and purification technology.

- Potentially useful for buyers that need a distributor-style commercial model with technical support.

Buyer considerations

Ask for the identity of the manufacturing site, whether it is the company's own facility, and whether the same source will be retained for future lots. Supplier consistency matters because a change in upstream producer can affect impurity profile, color, odor, solubility, and oxidation behavior.

8. Dalian Huihai Shengtong Biotechnology Co., Ltd.

Location: Dalian, Liaoning, China

Main focus: Functional peptides, cosmetic ingredients, research and industrial materials

Reported output: One public listing states 5,000 kg annual output for a glutathione-related product.

Dalian Huihai Shengtong Biotechnology is an export-oriented supplier positioned around high-grade peptide and functional raw-material categories. It may be relevant to buyers whose projects combine glutathione with peptides or require a supplier familiar with higher-value cosmetic active ingredients.

Key strengths

- Peptide and cosmetic-active orientation.

- Public product information references automated production lines, GMP-grade clean workshops, HPLC testing, heavy-metal testing, and microbial testing.

- Suitable for technically oriented buyers looking beyond commodity-grade ingredient supply.

Buyer considerations

Treat marketplace claims as preliminary. Verify the underlying analytical reports, laboratory accreditation where applicable, plant audit access, and the exact Reduced Glutathione assay method.

9. Xi'an Lyphar Biotech Co., Ltd.

Location: Xi'an, Shaanxi, China

Main focus: Plant extracts, nutraceutical ingredients, and custom/private-label support

Best fit: Buyers needing broader export-project coordination

Xi'an is one of China's better-known hubs for botanical extracts, with a dense supplier base for plant-derived ingredients, nutraceutical materials, and cosmetic actives. Xi'an Lyphar Biotech is often included in public lists of Chinese glutathione-related suppliers, although buyers should verify whether the company is the original GSH manufacturer for the offered batch.

Key strengths

- Potentially useful for buyers sourcing multiple plant-based and functional ingredients.

- Xi'an supply-chain access can support botanical-active development.

- Suitable for businesses that need sample coordination, private-label support, and combination ingredient procurement.

Buyer considerations

For an oxidation-sensitive biochemical ingredient such as GSH, direct manufacturing transparency is more important than a broad catalog. Request the name and address of the actual producer, batch COA, and a statement confirming whether the seller is authorized to distribute the material.

10. Shaanxi Guanjie Technology Co., Ltd.

Location: Shaanxi, China

Main focus: Botanical extracts, functional raw materials, and cosmetic/nutraceutical ingredient supply

Best fit: Multi-ingredient buyers exploring plant-active and antioxidant combinations

Shaanxi Guanjie Technology appears in public market lists of glutathione-related Chinese suppliers and operates in a region known for plant extract manufacturing. It may be relevant for buyers whose sourcing strategy includes both Reduced Glutathione and complementary plant actives.

Key strengths

- Regional access to botanical-extract supply chains.

- Potentially suitable for combined sourcing of antioxidant, brightening, and plant-derived materials.

- Commercial fit may be stronger for distributors and formulation companies than for high-volume single-ingredient procurement.

Buyer considerations

Verify whether the GSH is manufactured internally or supplied from an upstream fermentation producer. If it is sourced, ask whether the upstream manufacturer is fixed, approved, and subject to change-control procedures.

Common Sourcing Risks

1. Confusing GSH with GSSG

Reduced Glutathione and Oxidized Glutathione are not interchangeable. GSH is the reduced form; GSSG is the oxidized form. A supplier may offer both, and an ambiguous quotation can lead to purchasing the wrong material.

How to avoid it: State "L-Glutathione Reduced, CAS 70-18-8" in every RFQ, purchase order, and approved specification. Require the COA to show the assay and identification method.

2. Buying "99%" without knowing the test basis

A 99% figure can be reported on different bases, using different methods or calculations. It may not disclose moisture, related substances, GSSG content, or impurities.

How to avoid it: Request the full analytical method, chromatogram, reference standard information, and whether the result is reported on an as-is or dry basis.

3. Assuming a certificate covers the product

A valid ISO 9001 certificate may cover a company's quality-management system but not prove that a specific product is manufactured at a particular facility or meets a particular cosmetic-market requirement.

How to avoid it: Verify the certificate number through the issuing certification body. Check the company name, site address, certification scope, dates, and whether production—not only sales or trading—is included.

4. Overlooking oxidation during shipping

GSH can be affected by moisture, oxygen exposure, heat, and poor packaging. A good batch can lose quality if it is packed or shipped incorrectly.

How to avoid it: Confirm packaging material, moisture barrier, outer carton, desiccant, nitrogen flush where relevant, temperature requirements, and shipment lead time. Ask whether retain samples are kept for complaint investigations.

5. Treating cosmetic grade as a universal regulatory category

"Cosmetic grade" is often a commercial label, not a single globally harmonized legal standard. Compliance depends on the final product, concentration, target market, claims, impurity profile, and local notification or safety-assessment requirements.

How to avoid it: Build a market-specific documentation checklist for the EU, United States, United Kingdom, ASEAN, Middle East, or other target markets before final supplier approval.

An Industry Insider Tip

One frequently overlooked risk is the lag between COA testing and actual shipment.

Some suppliers test a bulk batch, issue a COA, and then repack or split the lot weeks later. For a relatively oxidation-sensitive material like Reduced Glutathione, the quality of the shipped packaging unit can differ from the original bulk sample if repacking conditions are not controlled.

Before placing a commercial order, ask:

- Is the COA generated from the exact finished packed lot?

- What is the date of manufacture and the date of analysis?

- Is the product repacked after testing?

- Is repacking done in a controlled environment?

- Can the supplier provide a retained sample from the final shipment lot?

- Will the batch number on the drum, COA, invoice, and packing list match exactly?

This question quickly separates suppliers with a controlled release process from suppliers relying mainly on generic paperwork.

Glutathione Quality Verification Process

Buyer's Verification Workflow

Step 1: Send a detailed RFQ

Include:

- Product: L-Glutathione Reduced / GSH

- CAS: 70-18-8

- Intended use: cosmetic ingredient, formulation development, finished-product manufacturing, or distribution

- Required assay and method

- Target market

- Annual estimated volume

- Preferred package size

- Required documents

- Sample quantity

- Delivery location and Incoterm

Step 2: Review technical documents

At minimum, request:

- COA for a recent batch

- TDS/specification sheet

- SDS

- HPLC chromatogram or test method summary

- Microbiological report

- Heavy-metals report

- Allergen, GMO, animal-origin, irradiation, and residual-solvent statements where relevant

- Certificate copies with expiry dates

- Country-of-origin statement

- Packaging and storage statement

Step 3: Qualify a sample

Do not approve solely by appearance. Conduct at least:

- Identity confirmation

- Assay verification through a qualified third-party laboratory

- Solubility and odor assessment

- Color stability review

- Compatibility testing in the intended formulation

- Accelerated stability screening where appropriate

Step 4: Audit commercial reliability

For higher-volume projects, evaluate:

- Video audit of the production and packing area

- Batch traceability process

- Change-control policy

- Complaint-handling procedure

- Lead-time commitment

- Export documentation experience

- Insurance, payment terms, and shipment controls

Step 5: Protect the first commercial order

Use a clear purchase specification and quality agreement. Consider third-party pre-shipment inspection or independent lab testing for the first commercial batch, especially when the material will be used in high-value skincare, ingestible, or pharmaceutical-adjacent applications.

Conclusion

China offers a broad range of Reduced Glutathione suppliers—from large fermentation-oriented biochemical producers to flexible cosmetic-active partners. The right choice depends on whether your priority is large-volume supply, technical documentation, derivative forms, small-batch development, or integrated OEM/ODM support.

For brands and formulators seeking a responsive partner for cosmetic-active projects, ZHENYIBIO TECHNOLOGY INC is worth considering as a flexible, R&D-oriented supplier with experience across glutathione, peptides, liposomes, hyaluronic acid, polyglutamic acid, and botanical cosmetic ingredients. Its positioning is especially relevant for small and mid-sized brands that need practical communication, sample-stage support, and customized project coordination rather than a purely commodity-based transaction.

Request a current specification, recent batch COA, sample, and documentation package before placing a commercial order. This is the most reliable way to compare suppliers on real performance rather than catalog claims.

Frequently Asked Questions

1. How can I verify whether an ISO certificate has expired?

Ask the supplier for the complete certificate, including certificate number, issuing certification body, certified company name, site address, scope, issue date, and expiry date. Then verify it through the issuing body's public certificate database or direct written inquiry. Do not rely on a cropped image or an untranslated certificate alone.

2. Is 99% Reduced Glutathione always suitable for cosmetic use?

No. Assay is only one factor. You should also assess identity, GSSG content, heavy metals, microbiological limits, residual solvents, packaging, stability, traceability, and regulatory suitability for the intended market. A high assay result does not automatically prove formulation compatibility or legal acceptability.

3. What sample quantity should I request before placing an order?

For basic laboratory screening, 10–50 g may be enough. For formulation trials, accelerated stability tests, and third-party analysis, 100–500 g is more practical. If you need pilot production, request a pre-commercial sample that is packed from a representative production lot.

4. Can a Chinese supplier provide OEM or ODM support for glutathione skincare products?

Yes, but the scope varies widely. Some companies only supply bulk GSH powder; others can help with ingredient combinations, prototype development, packaging, private labeling, and finished-product manufacturing. Confirm whether the supplier has its own formulation and production capability or relies on partner factories. ZHENYIBIO is positioned toward cosmetic active-material solutions and can be considered by brands that need ingredient coordination alongside OEM/ODM-oriented project support.

5. What is the most important contract term for Reduced Glutathione procurement?

Attach a detailed product specification to the purchase order or quality agreement. It should define product identity, assay method, acceptance limits, impurity and microbial limits, packaging, storage, shelf life, batch documentation, sampling method, non-conformance handling, and the process for supplier changes. A quotation alone is not enough.